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Research Article

Prophylactic Perioperative Sodium Bicarbonate to Prevent Acute Kidney Injury Following Open Heart Surgery: A Multicenter Double-Blinded Randomized Controlled Trial

  • Michael Haase equal contributor,

    equal contributor Contributed equally to this work with: Michael Haase, Anja Haase-Fielitz

    Affiliation: Department of Nephrology and Hypertension, Diabetes, and Endocrinology, Otto-von-Guericke-University Magdeburg, Germany

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  • Anja Haase-Fielitz equal contributor mail,

    equal contributor Contributed equally to this work with: Michael Haase, Anja Haase-Fielitz

    anja.haase-fielitz@med.ovgu.de (AHF); Rinaldo.Bellomo@austin.org.au (RB)

    Affiliation: Department of Nephrology and Hypertension, Diabetes, and Endocrinology, Otto-von-Guericke-University Magdeburg, Germany

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  • Michael Plass,

    Affiliation: Department of Anesthesiology, The German Heart Center, Berlin, Germany

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  • Hermann Kuppe,

    Affiliation: Department of Anesthesiology, The German Heart Center, Berlin, Germany

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  • Roland Hetzer,

    Affiliation: Department of Cardiothoracic Surgery, The German Heart Center, Berlin, Germany

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  • Claire Hannon,

    Affiliation: Nephrology and Clinical Pharmacology, University College Dublin School of Medicine and Medical Science, Dublin, Ireland

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  • Patrick T. Murray,

    Affiliation: Nephrology and Clinical Pharmacology, University College Dublin School of Medicine and Medical Science, Dublin, Ireland

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  • Michael J. Bailey,

    Affiliation: The Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia

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  • Rinaldo Bellomo mail,

    anja.haase-fielitz@med.ovgu.de (AHF); Rinaldo.Bellomo@austin.org.au (RB)

    Affiliation: Department of Intensive Care, The Austin Hospital, Melbourne, Australia

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  • Sean M. Bagshaw

    Affiliation: Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Alberta, Canada

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  • Published: April 16, 2013
  • DOI: 10.1371/journal.pmed.1001426

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