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Research Article

Stress-Mediated Increases in Systemic and Local Epinephrine Impair Skin Wound Healing: Potential New Indication for Beta Blockers

  • Raja K Sivamani,

    Affiliation: Department of Dermatology, University of California, Davis, School of Medicine, Davis, California, United States of America

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  • Christine E Pullar,

    Affiliation: Department of Dermatology, University of California, Davis, School of Medicine, Davis, California, United States of America

    ¤ Current address: Department of Cell Physiology and Pharmacology, University of Leicester, United Kingdom

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  • Catherine G Manabat-Hidalgo,

    Affiliation: Department of Dermatology, University of California, Davis, School of Medicine, Davis, California, United States of America

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  • David M Rocke,

    Affiliation: Division of Biostatistics, University of California, Davis, School of Medicine, Davis, California, United States of America

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  • Richard C Carlsen,

    Affiliation: Department of Physiology and Membrane Biology, University of California, Davis, School of Medicine, Davis, California, United States of America

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  • David G Greenhalgh,

    Affiliations: Department of Surgery, University of California, Davis, School of Medicine, Davis, California, United States of America, Shriners Hospitals for Children Northern California, Sacramento, California, United States of America

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  • R. Rivkah Isseroff mail

    To whom correspondence should be addressed. E-mail: rrisseroff@ucdavis.edu

    Affiliations: Department of Dermatology, University of California, Davis, School of Medicine, Davis, California, United States of America, Shriners Hospitals for Children Northern California, Sacramento, California, United States of America, Wound Service, Department of Veterans Affairs, Northern California Health Care System, Mather, California, United States of America

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  • Published: January 13, 2009
  • DOI: 10.1371/journal.pmed.1000012

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