Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells

Hendrik Streeck; Zabrina L Brumme; Michael Anastario; Kristin W Cohen; Jonathan S Jolin; Angela Meier; Chanson J Brumme; Eric S Rosenberg; Galit Alter; Todd M Allen; Bruce D Walker; Marcus Altfeld

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Published in the May 2008 Issue of PLoS Medicine

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Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8⁺ T Cells