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Research Article

Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

  • Paul W Denton,

    Affiliation: Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Jacob D Estes,

    Affiliation: Department of Microbiology, Medical School, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Zhifeng Sun,

    Affiliation: Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Florence A Othieno,

    Affiliation: Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Bangdong L Wei,

    Affiliation: Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Anja K Wege,

    Affiliation: Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Daniel A Powell,

    Affiliation: Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Deborah Payne,

    Affiliation: Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Ashley T Haase,

    Affiliation: Department of Microbiology, Medical School, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • J. Victor Garcia mail

    To whom correspondence should be addressed. E-mail: victor.garcia@utsouthwestern.edu

    Affiliation: Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, United States of America

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  • Published: January 15, 2008
  • DOI: 10.1371/journal.pmed.0050016

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Linked Articles

Can the New Humanized Mouse Model Give HIV Research a Boost?

Barbara L Shacklett
Perspective | published 15 Jan 2008 | PLOS Medicine
doi:10.1371/journal.pmed.0050013