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Research Article

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1

  • Marcus Altfeld mail,

    To whom correspondence should be addressed. E-mail: maltfeld@partners.org

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

    X
  • Elizabeth T Kalife,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

    X
  • Ying Qi,

    Affiliation: Basic Research Program, SAIC-Frederick, Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America

    X
  • Hendrik Streeck,

    Affiliations: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America, Gemeinschaftspraxis Jessen, Berlin, Germany

    X
  • Mathias Lichterfeld,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

    X
  • Mary N Johnston,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

    X
  • Nicole Burgett,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

    X
  • Martha E Swartz,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

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  • Amy Yang,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

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  • Galit Alter,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

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  • Xu G Yu,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

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  • Angela Meier,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

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  • Juergen K Rockstroh,

    Affiliation: Department of Internal Medicine, University of Bonn, Bonn, Germany

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  • Todd M Allen,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

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  • Heiko Jessen,

    Affiliation: Gemeinschaftspraxis Jessen, Berlin, Germany

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  • Eric S Rosenberg,

    Affiliation: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

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  • Mary Carrington,

    Affiliation: Basic Research Program, SAIC-Frederick, Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America

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  • Bruce D Walker

    Affiliations: Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

    X
  • Published: October 31, 2006
  • DOI: 10.1371/journal.pmed.0030403

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