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Research Article

Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans

  • Samir M Parikh equal contributor,

    equal contributor Contributed equally to this work with: Samir M Parikh, Tadanori Mammoto

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Tadanori Mammoto equal contributor,

    equal contributor Contributed equally to this work with: Samir M Parikh, Tadanori Mammoto

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Aylit Schultz,

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Hai-Tao Yuan,

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • David Christiani,

    Affiliation: Occupational Health Program, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • S. Ananth Karumanchi,

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Vikas P Sukhatme mail

    To whom correspondence should be addressed. E-mail: vsukhatm@bidmc.harvard.edu

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: January 24, 2006
  • DOI: 10.1371/journal.pmed.0030046

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Linked Articles

Angiopoietin-2: Modulator of Vascular Permeability in Acute Lung Injury?

Tomoki Hashimoto, Jean-Francois Pittet
Perspective | published 7 Feb 2006 | PLOS Medicine
doi:10.1371/journal.pmed.0030113

Angiopoietin-2: A New Therapeutic Target for Preventing Lung Dysfunction in Sepsis?

Synopsis | published 24 Jan 2006 | PLOS Medicine
doi:10.1371/journal.pmed.0030097