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Research Article

Interleukin-1 Stimulates β-Cell Necrosis and Release of the Immunological Adjuvant HMGB1

  • Sarah A Steer,

    Affiliation: The Edward A. Doisy Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St. Louis, Missouri, United States of America

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  • Anna L Scarim,

    Affiliation: The Edward A. Doisy Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St. Louis, Missouri, United States of America

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  • Kari T Chambers,

    Affiliation: The Edward A. Doisy Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St. Louis, Missouri, United States of America

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  • John A Corbett mail

    To whom correspondence should be addressed. E-mail: corbettj@slu.edu

    Affiliation: The Edward A. Doisy Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St. Louis, Missouri, United States of America

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  • Published: December 20, 2005
  • DOI: 10.1371/journal.pmed.0030017

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