Advertisement
Research Article

Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

  • Peter Recknagel equal contributor,

    equal contributor Contributed equally to this work with: Peter Recknagel, Falk A. Gonnert

    Affiliations: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany, Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom

    X
  • Falk A. Gonnert equal contributor,

    equal contributor Contributed equally to this work with: Peter Recknagel, Falk A. Gonnert

    Affiliation: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany

    X
  • Martin Westermann,

    Affiliation: Electron Microscopy Center, Jena University Hospital, Jena, Germany

    X
  • Sandro Lambeck,

    Affiliation: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany

    X
  • Amelie Lupp,

    Affiliation: Department of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany

    X
  • Alain Rudiger,

    Affiliation: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom

    X
  • Alex Dyson,

    Affiliation: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom

    X
  • Jane E. Carré,

    Affiliation: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom

    X
  • Andreas Kortgen,

    Affiliation: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany

    X
  • Christoph Krafft,

    Affiliation: Institute of Photonic Technology, Jena, Germany

    X
  • Jürgen Popp,

    Affiliation: Institute of Photonic Technology, Jena, Germany

    X
  • Christoph Sponholz,

    Affiliation: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany

    X
  • Valentin Fuhrmann,

    Affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

    X
  • Ingrid Hilger,

    Affiliation: Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany

    X
  • Ralf A. Claus,

    Affiliation: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany

    X
  • Niels C. Riedemann,

    Affiliation: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany

    X
  • Reinhard Wetzker,

    Affiliation: Department of Molecular Cell Biology, Center for Molecular Biomedicine, Jena University Hospital, Jena, Germany

    X
  • Mervyn Singer,

    Affiliation: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom

    X
  • Michael Trauner ,

    Affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

    These authors are joint senior authors on this work.

    X
  • Michael Bauer mail

    Michael.Bauer@med.uni-jena.de

    Affiliation: Integrated Research and Treatment Center, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany

    These authors are joint senior authors on this work.

    X
  • Published: November 13, 2012
  • DOI: 10.1371/journal.pmed.1001338

Viewed info

Cited info

Saved info

Discussed info

Questions or concerns about usage data? Please let us know.