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Research Article

Vitamin K Supplementation in Postmenopausal Women with Osteopenia (ECKO Trial): A Randomized Controlled Trial

  • Angela M Cheung mail,

    To whom correspondence should be addressed. E-mail: angela.cheung@uhn.on.ca

    Affiliations: Division of General Internal Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Division of Endocrinology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Clinical Epidemiology Program, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, Osteoporosis and Women's Health Programs, University Health Network, Toronto, Ontario, Canada

    X
  • Lianne Tile,

    Affiliations: Division of General Internal Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Osteoporosis and Women's Health Programs, University Health Network, Toronto, Ontario, Canada

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  • Yuna Lee,

    Affiliation: Division of General Internal Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

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  • George Tomlinson,

    Affiliations: Division of General Internal Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Clinical Epidemiology Program, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada

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  • Gillian Hawker,

    Affiliations: Clinical Epidemiology Program, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, Division of Rheumatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

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  • Judy Scher,

    Affiliation: Osteoporosis and Women's Health Programs, University Health Network, Toronto, Ontario, Canada

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  • Hanxian Hu,

    Affiliation: Osteoporosis and Women's Health Programs, University Health Network, Toronto, Ontario, Canada

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  • Reinhold Vieth,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Toronto, Toronto, Ontario, Canada

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  • Lilian Thompson,

    Affiliation: Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada

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  • Sophie Jamal,

    Affiliations: Division of Endocrinology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Clinical Epidemiology Program, Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada

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  • Robert Josse

    Affiliation: Division of Endocrinology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

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  • Published: October 14, 2008
  • DOI: 10.1371/journal.pmed.0050196

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