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Research Article

Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity

  • Kirsi H Pietiläinen equal contributor,

    equal contributor Contributed equally to this work with: Kirsi H Pietiläinen, Jussi Naukkarinen

    Affiliations: Obesity Research Unit, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland, Department of Medicine, Division of Diabetes, Helsinki University Central Hospital, Helsinki, Finland, Finnish Twin Cohort Study, Department of Public Health, University of Helsinki, Helsinki, Finland

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  • Jussi Naukkarinen equal contributor,

    equal contributor Contributed equally to this work with: Kirsi H Pietiläinen, Jussi Naukkarinen

    Affiliations: Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, Department of Medical Genetics and Research Program of Molecular Medicine, University of Helsinki, Finland

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  • Aila Rissanen,

    Affiliation: Obesity Research Unit, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland

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  • Juha Saharinen,

    Affiliations: Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, Department of Medical Genetics and Research Program of Molecular Medicine, University of Helsinki, Finland

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  • Pekka Ellonen,

    Affiliations: Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, Department of Medical Genetics and Research Program of Molecular Medicine, University of Helsinki, Finland

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  • Heli Keränen,

    Affiliations: Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, Department of Medical Genetics and Research Program of Molecular Medicine, University of Helsinki, Finland

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  • Anu Suomalainen,

    Affiliation: Research Program of Molecular Neurology and Department of Neurology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland

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  • Alexandra Götz,

    Affiliation: Research Program of Molecular Neurology and Department of Neurology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland

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  • Tapani Suortti,

    Affiliation: VTT Technical Research Centre of Finland, Espoo, Finland

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  • Hannele Yki-Järvinen,

    Affiliation: Department of Medicine, Division of Diabetes, Helsinki University Central Hospital, Helsinki, Finland

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  • Matej Orešič,

    Affiliation: VTT Technical Research Centre of Finland, Espoo, Finland

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  • Jaakko Kaprio,

    Affiliations: Finnish Twin Cohort Study, Department of Public Health, University of Helsinki, Helsinki, Finland, Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland

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  • Leena Peltonen mail

    To whom correspondence should be addressed. E-mail: leena.peltonen@ktl.fi

    Affiliations: Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, Department of Medical Genetics and Research Program of Molecular Medicine, University of Helsinki, Finland, The Wellcome Trust Sanger Institute, Cambridge, United Kingdom, Broad Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Published: March 11, 2008
  • DOI: 10.1371/journal.pmed.0050051

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