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Research Article

Targeting of Interferon-Beta to Produce a Specific, Multi-Mechanistic Oncolytic Vaccinia Virus

  • David H Kirn,

    Affiliations: Jennerex Biotherapeutics, San Francisco, California, United States of America, Clinical Pharmacology, University of Oxford, Oxford, United Kingdom

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  • Yaohe Wang,

    Affiliation: Cancer Research UK Molecular Oncology Centre, Queen Mary's School of Medicine and Dentistry, Charterhouse Square, London, United Kingdom

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  • Fabrice Le Boeuf,

    Affiliation: Ottawa Health Research Institute, Ottawa, Ontario, Canada

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  • John Bell,

    Affiliation: Ottawa Health Research Institute, Ottawa, Ontario, Canada

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  • Steve H Thorne mail

    To whom correspondence should be addressed. E-mail: thornesh@upmc.edu

    Affiliations: Jennerex Biotherapeutics, San Francisco, California, United States of America, Department of Pediatrics and Bio-X Program, Stanford University, Stanford, California, United States of America

    ¤ Current address: Division of Surgical Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Published: December 27, 2007
  • DOI: 10.1371/journal.pmed.0040353

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