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Research Article

NSAIDs Modulate CDKN2A, TP53, and DNA Content Risk for Progression to Esophageal Adenocarcinoma

  • Patricia C Galipeau equal contributor mail,

    equal contributor Contributed equally to this work with: Patricia C Galipeau, Xiaohong Li

    To whom correspondence should be addressed. E-mail: pgal@fhcrc.org

    Affiliations: Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

    X
  • Xiaohong Li equal contributor,

    equal contributor Contributed equally to this work with: Patricia C Galipeau, Xiaohong Li

    Affiliation: Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

    X
  • Patricia L Blount,

    Affiliations: Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America

    X
  • Carlo C Maley,

    Affiliation: Cellular and Molecular Oncogenesis Program, Wistar Institute, Philadelphia, Pennsylvania, United States of America

    X
  • Carissa A Sanchez,

    Affiliations: Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

    X
  • Robert D Odze,

    Affiliation: Department of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America

    X
  • Kamran Ayub,

    Affiliation: Department of Gastroenterology, Virginia Mason Medical Center, Seattle, Washington, United States of America

    X
  • Peter S Rabinovitch,

    Affiliations: Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Pathology, University of Washington, Seattle, Washington, United States of America

    X
  • Thomas L Vaughan,

    Affiliations: Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Epidemiology, University of Washington, Seattle, Washington, United States of America

    X
  • Brian J Reid

    Affiliations: Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Genome Sciences, University of Washington, Seattle, Washington, United States of America

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  • Published: February 27, 2007
  • DOI: 10.1371/journal.pmed.0040067

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