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Research Article

Does Random Treatment Assignment Cause Harm to Research Participants?

  • Cary P Gross mail,

    To whom correspondence should be addressed. E-mail: cary.gross@yale.edu

    Affiliations: Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America, Robert Wood Johnson Clinical Scholars Program, Yale School of Medicine, New Haven, Connecticut, United States of America

    X
  • Harlan M Krumholz,

    Affiliations: Section of General Internal Medicine and Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America, Robert Wood Johnson Clinical Scholars Program, Yale School of Medicine, New Haven, Connecticut, United States of America, Section of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, United States of America

    X
  • Gretchen Van Wye,

    Affiliation: Section of Chronic Disease Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, United States of America

    X
  • Ezekiel J Emanuel,

    Affiliation: Department of Clinical Bioethics, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America

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  • David Wendler

    Affiliation: Department of Clinical Bioethics, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: June 06, 2006
  • DOI: 10.1371/journal.pmed.0030188

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