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Research Article

Prevention of SIV Rectal Transmission and Priming of T Cell Responses in Macaques after Local Pre-exposure Application of Tenofovir Gel

  • Martin Cranage mail,

    To whom correspondence should be addressed. E-mail: mcranage@sgul.ac.uk

    Affiliation: Centre for Infection, Division of Cellular & Molecular Medicine, St George's University of London, London, United Kingdom

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  • Sally Sharpe,

    Affiliation: Centre for Emergency Preparedness and Response, Health Protection Agency, Porton Down, Salisbury, United Kingdom

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  • Carolina Herrera,

    Affiliation: Centre for Infection, Division of Cellular & Molecular Medicine, St George's University of London, London, United Kingdom

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  • Alethea Cope,

    Affiliation: Centre for Infection, Division of Cellular & Molecular Medicine, St George's University of London, London, United Kingdom

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  • Mike Dennis,

    Affiliation: Centre for Emergency Preparedness and Response, Health Protection Agency, Porton Down, Salisbury, United Kingdom

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  • Neil Berry,

    Affiliation: Division of Retrovirology, National Institute for Biological Standards & Control, South Mimms, United Kingdom

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  • Claire Ham,

    Affiliation: Division of Retrovirology, National Institute for Biological Standards & Control, South Mimms, United Kingdom

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  • Jonathan Heeney,

    Affiliations: Department of Virology, Biomedical Primate Research Centre, Rijswijk, The Netherlands, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

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  • Naser Rezk,

    Affiliation: University of North Carolina Centers for Aids Research (CFAR) Clinical Pharmacology and Analytical Chemistry Core, Chapel Hill, North Carolina, United States of America

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  • Angela Kashuba,

    Affiliation: University of North Carolina Centers for Aids Research (CFAR) Clinical Pharmacology and Analytical Chemistry Core, Chapel Hill, North Carolina, United States of America

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  • Peter Anton,

    Affiliation: Center for Prevention Research, David Geffen School of Medicine at the University of California Los Angeles (UCLA), Los Angeles, California, United States of America

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  • Ian McGowan,

    Affiliation: Center for Prevention Research, David Geffen School of Medicine at the University of California Los Angeles (UCLA), Los Angeles, California, United States of America

    ¤ Current address: Magee Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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  • Robin Shattock

    Affiliation: Centre for Infection, Division of Cellular & Molecular Medicine, St George's University of London, London, United Kingdom

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  • Published: August 05, 2008
  • DOI: 10.1371/journal.pmed.0050157

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