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Research Article

HIV Patients Developing Primary CNS Lymphoma Lack EBV-Specific CD4+ T Cell Function Irrespective of Absolute CD4+ T Cell Counts

  • Olivier Gasser,

    Affiliation: Immunobiology Laboratory, Department of Research, University Hospital Basel, Basel, Switzerland

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  • Florian K Bihl,

    Affiliation: Partners AIDS Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Marcel Wolbers,

    Affiliation: Institute for Clinical Epidemiology, University Hospital Basel, Basel, Switzerland

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  • Elisabetta Loggi,

    Affiliation: Partners AIDS Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Ingrid Steffen,

    Affiliation: Institute for Medical Microbiology, University of Basel, Basel, Switzerland

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  • Hans H Hirsch,

    Affiliation: Institute for Medical Microbiology, University of Basel, Basel, Switzerland

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  • Huldrych F Günthard,

    Affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, Zürich, Switzerland

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  • Bruce D Walker,

    Affiliation: Partners AIDS Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Christian Brander,

    Affiliation: Partners AIDS Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Manuel Battegay,

    Affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland

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  • Christoph Hess mail,

    To whom correspondence should be addressed. E-mail: chess@uhbs.ch

    Affiliation: Immunobiology Laboratory, Department of Research, University Hospital Basel, Basel, Switzerland

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  • for the Swiss HIV Cohort Study
  • Published: March 27, 2007
  • DOI: 10.1371/journal.pmed.0040096

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