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Research Article

Abnormal Cortical Development after Premature Birth Shown by Altered Allometric Scaling of Brain Growth

  • Olga Kapellou,

    Affiliation: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom

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  • Serena J Counsell,

    Affiliation: Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • Nigel Kennea,

    Affiliation: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom

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  • Leigh Dyet,

    Affiliations: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom, Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • Nadeem Saeed,

    Affiliation: Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • Jaroslav Stark,

    Affiliation: Department of Mathematics, Imperial College, London, United Kingdom

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  • Elia Maalouf,

    Affiliation: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom

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  • Philip Duggan,

    Affiliation: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom

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  • Morenike Ajayi-Obe,

    Affiliation: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom

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  • Jo Hajnal,

    Affiliation: Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • Joanna M Allsop,

    Affiliation: Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • James Boardman,

    Affiliations: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom, Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • Mary A Rutherford,

    Affiliation: Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • Frances Cowan,

    Affiliations: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom, Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • A. David Edwards mail

    To whom correspondence should be addressed. E-mail: david.edwards@imperial.ac.uk

    Affiliations: Department of Paediatrics, Imperial College, Hammersmith Hospital, London, United Kingdom, Division of Clinical Sciences, Imperial College, and MRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

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  • Published: August 01, 2006
  • DOI: 10.1371/journal.pmed.0030265

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