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Research Article

Stage-Specific Action of Matrix Metalloproteinases Influences Progressive Hereditary Kidney Disease

  • Michael Zeisberg,

    Affiliation: Center for Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Mona Khurana,

    Affiliation: Center for Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Velidi H Rao,

    Affiliation: Gene Expression Laboratory, Boys Town National Research Hospital, Omaha, Nebraska, United States of America

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  • Dominic Cosgrove,

    Affiliation: Gene Expression Laboratory, Boys Town National Research Hospital, Omaha, Nebraska, United States of America

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  • Jean-Philippe Rougier,

    Affiliation: Department of Anatomy, University of California San Francisco, San Francisco, California, United States of America

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  • Michelle C Werner,

    Affiliation: Center for Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Charles F Shield III,

    Affiliation: Department of Surgery, University of Kansas School of Medicine, Wichita, Kansas, United States of America

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  • Zena Werb,

    Affiliation: Department of Anatomy, University of California San Francisco, San Francisco, California, United States of America

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  • Raghu Kalluri mail

    To whom correspondence should be addressed. E-mail: rkalluri@bidmc.harvard.edu

    Affiliations: Center for Matrix Biology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Harvard–MIT Division of Health Sciences and Technology, Boston, Massachusetts, United States of America, Division of Nephrology, Children's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: March 07, 2006
  • DOI: 10.1371/journal.pmed.0030100

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