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Research Article

Are Anticapsular Antibodies the Primary Mechanism of Protection against Invasive Pneumococcal Disease?

  • Marc Lipsitch mail,

    To whom correspondence should be addressed. E-mail: mlipsitc@hsph.harvard.edu

    Affiliation: Departments of Epidemiology and Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, United States of America

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  • Cynthia G Whitney,

    Affiliation: Active Bacterial Core Surveillance and Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Elizabeth Zell,

    Affiliation: Active Bacterial Core Surveillance and Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Tarja Kaijalainen,

    Affiliation: National Reference Laboratory for Pneumococcus, National Public Health Institute, Oulu, Finland

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  • Ron Dagan,

    Affiliation: Pediatric Infectious Disease Unit, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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  • Richard Malley

    Affiliation: Children's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: January 25, 2005
  • DOI: 10.1371/journal.pmed.0020015

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