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Editorial
The PLoS Medicine Debate
Essays
Perspectives
Policy Forums
Research in Translation
Best Practice
Student Forum
Research Articles
Correspondence
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Table of Contents | October 2006

About This Image

Social Medicine across the Ages.

The cover image takes its theme from Dorothy Porter's article, which looks at the historical roots of social medicine and asks where it is heading. The article is part of a special collection of eleven magazine pieces and five original research papers examining social and cultural aspects of medicine and health and the socioeconomic determinants of disease.

Image Credit: Cover design by Natalie Davis, Public Library of Science, with images from the US Library of Congress (an image used by Dorothy Porter in her article) and Tavis Ford

Editorial

Social Medicine in the Twenty-First Century

Scott Stonington, Seth M Holmes

The PLoS Medicine Debate

Is It Ethical for Patients with Renal Disease to Purchase Kidneys from the World's Poor?

Tarif Bakdash, Nancy Scheper-Hughes

Essays

Health Is Still Social: Contemporary Examples in the Age of the Genome

Timothy H Holtz, Seth Holmes, Scott Stonington, Leon Eisenberg

How Did Social Medicine Evolve, and Where Is It Heading?

Dorothy Porter

Anthropology in the Clinic: The Problem of Cultural Competency and How to Fix It

Arthur Kleinman, Peter Benson

“Anecdotal Evidence”: Why Narratives Matter to Medical Practice

Rafael Campo

Is There a Global Bioethics? End-of-Life in Thailand and the Case for Local Difference

Scott Stonington, Pinit Ratanakul

Ethnic Disparities in Health: The Public's Role in Working for Equality

David Satcher

Five Myths about the HIV Epidemic in Asia

Peter Godwin, Nigel O'Farrell, Knut Fylkesnes, Sujaya Misra

HIV, Stigma, and Rates of Infection: A Rumour without Evidence

Daniel D Reidpath, Kit Yee Chan

Perspectives

How Important Is Diabetes as a Risk Factor for Cardiovascular and Other Diseases in Older Adults?

Andre Pascal Kengne, Anushka Patel

Can the Severity of Normal Tissue Damage after Radiation Therapy Be Predicted?

Adrian C Begg

The Migrainous Brain: What You See Is Not All You Get?

Peter J Goadsby

Can We Prevent, Delay, or Shorten the Course of Dementia?

Willem A Van Gool

Complement Factor H Gene Abnormalities in Haemolytic Uraemic Syndrome: From Point Mutations to Hybrid Gene

Marina Noris, Giuseppe Remuzzi

Policy Forums

Structural Violence and Clinical Medicine

Paul E Farmer, Bruce Nizeye, Sara Stulac, Salmaan Keshavjee

Time to Regenerate: Ecosystems and Health Promotion

Colin D Butler, Sharon Friel

Priority Setting for Pandemic Influenza: An Analysis of National Preparedness Plans

Lori Uscher-Pines, Saad B Omer, Daniel J Barnett, Thomas A Burke, Ran D Balicer

Estimating the Demand for a Preventive HIV Vaccine: Why We Need to Do Better

Robert Hecht, Chutima Suraratdecha

Responding to AIDS, Tuberculosis, Malaria, and Emerging Infectious Diseases in Burma: Dilemmas of Policy and Practice

Chris Beyrer, Voravit Suwanvanichkij, Luke C Mullany, Adam K Richards, Nicole Franck, Aaron Samuels, Thomas J Lee

Research in Translation

HIV-1 Viral Load Assays for Resource-Limited Settings

Susan A Fiscus, Ben Cheng, Suzanne M Crowe, Lisa Demeter, Cheryl Jennings, Veronica Miller, Richard Respess, Wendy Stevens

Best Practice

Antidepressant Prevention of Postnatal Depression

Louise M Howard, Elizabeth Boath, Carol Henshaw

Student Forum

Why Should Medical Students Care about Health Policy?

Rajesh Gupta

Research Articles

Reconstructing Tuberculosis Services after Major Conflict: Experiences and Lessons Learned in East Timor

Nelson Martins, Paul M Kelly, Jocelyn A Grace, Anthony B Zwi

Insights into the Management of Emerging Infections: Regulating Variant Creutzfeldt-Jakob Disease Transfusion Risk in the UK and the US

Maya L Ponte

An Ethnographic Study of the Social Context of Migrant Health in the United States

Seth M Holmes

Indigenous Health and Socioeconomic Status in India

S. V Subramanian, George Davey Smith, Malavika Subramanyam

Reinterpreting Ethnic Patterns among White and African American Men Who Inject Heroin: A Social Science of Medicine Approach

Philippe Bourgois, Alexis Martinez, Alex Kral, Brian R Edlin, Jeff Schonberg, Dan Ciccarone

A Comparative Analysis of Influenza Vaccination Programs

Shweta Bansal, Babak Pourbohloul, Lauren Ancel Meyers

Empirical Evidence for the Effect of Airline Travel on Inter-Regional Influenza Spread in the United States

John S Brownstein, Cecily J Wolfe, Kenneth D Mandl

Tuberculosis Recurrence and Mortality after Successful Treatment: Impact of Drug Resistance

Helen Cox, Yared Kebede, Sholpan Allamuratova, Gabit Ismailov, Zamira Davletmuratova, Graham Byrnes, Christine Stone, Stefan Niemann, Sabine Rüsch-Gerdes, Lucie Blok, Daribay Doshetov

Cost-Effectiveness Study of Three Antimalarial Drug Combinations in Tanzania

Virginia Wiseman, Michelle Kim, Theonest K Mutabingwa, Christopher J. M Whitty

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8⁺ T Cell Response against HIV-1

Marcus Altfeld, Elizabeth T Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N Johnston, Nicole Burgett, Martha E Swartz, Amy Yang, Galit Alter, Xu G Yu, Angela Meier, Juergen K Rockstroh, Todd M Allen, Heiko Jessen, Eric S Rosenberg, Mary Carrington, Bruce D Walker

Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer

Anju Singh, Vikas Misra, Rajesh K Thimmulappa, Hannah Lee, Stephen Ames, Mohammad O Hoque, James G Herman, Stephen B Baylin, David Sidransky, Edward Gabrielson, Malcolm V Brock, Shyam Biswal

Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction

Michael N Weedon, Mark I McCarthy, Graham Hitman, Mark Walker, Christopher J Groves, Eleftheria Zeggini, N. William Rayner, Beverley Shields, Katharine R Owen, Andrew T Hattersley, Timothy M Frayling

Mortality in Pharmacologically Treated Older Adults with Diabetes: The Cardiovascular Health Study, 1989–2001

Richard A Kronmal, Joshua I Barzilay, Nicholas L Smith, Bruce M Psaty, Lewis H Kuller, Gregory L Burke, Curt Furberg

Lentiviral Gene Transfer of Rpe65 Rescues Survival and Function of Cones in a Mouse Model of Leber Congenital Amaurosis

Alexis-Pierre Bemelmans, Corinne Kostic, Sylvain V Crippa, William W Hauswirth, Janis Lem, Francis L Munier, Mathias W Seeliger, Andreas Wenzel, Yvan Arsenijevic

Analysis of Gene Expression Using Gene Sets Discriminates Cancer Patients with and without Late Radiation Toxicity

J. Peter Svensson, Lukas J. A Stalpers, Rebecca E. E. Esveldt–van Lange, Nicolaas A. P Franken, Jaap Haveman, Binie Klein, Ingela Turesson, Harry Vrieling, Micheline Giphart-Gassler

Anatomical Alterations of the Visual Motion Processing Network in Migraine with and without Aura

Cristina Granziera, Alexandre F. M DaSilva, Josh Snyder, David S Tuch, Nouchine Hadjikhani

Dementia before Death in Ageing Societies— The Promise of Prevention and the Reality

Carol Brayne, Lu Gao, Michael Dewey, Fiona E Matthews

Methods of Blinding in Reports of Randomized Controlled Trials Assessing Pharmacologic Treatments: A Systematic Review

Isabelle Boutron, Candice Estellat, Lydia Guittet, Agnes Dechartres, David L Sackett, Asbjørn Hróbjartsson, Philippe Ravaud

A Population-Based Study on Alcohol and High-Risk Sexual Behaviors in Botswana

Sheri D Weiser, Karen Leiter, Michele Heisler, Willi McFarland, Fiona Percy-de Korte, Sonya M DeMonner, Sheila Tlou, Nthabiseng Phaladze, Vincent Iacopino, David R Bangsberg

Time to Renal Disease and End-Stage Renal Disease in PROFILE: A Multiethnic Lupus Cohort

Graciela S Alarcón, Gerald McGwin Jr., Michelle Petri, Rosalind Ramsey-Goldman, Barri J Fessler, Luis M Vilá, Jeffrey C Edberg, John D Reveille, Robert P Kimberly

Atypical Haemolytic Uraemic Syndrome Associated with a Hybrid Complement Gene

Julian P Venables, Lisa Strain, Danny Routledge, David Bourn, Helen M Powell, Paul Warwicker, Martha L Diaz-Torres, Anne Sampson, Paul Mead, Michelle Webb, Yves Pirson, Michael S Jackson, Anne Hughes, Katrina M Wood, Judith A Goodship, Timothy H. J Goodship