Table of Contents: October 2005



Image Credit: Rob Frankle (
Issue Image

Rob Frankle is an illustrator and graphic designer. In both disciplines, his goal is to communicate issues with simplicity and psychological impact. He believes that the process of painting is a dialogue between external and internal reality. From childhood, he has always been fascinated with how marks on paper can often reach below the surface of experience and connect with viewers. In this painting, Frankle focuses on the common yet not fully understood condition we call "dementia." The main symptom of dementia is an acute decline in mental ability. With this, an upheaval of personal reality occurs. One's normal construct of time and place often dissolves. Dementia dramatically reveals to us the critical nature of brain function in defining our reality.

Frankle holds a B. F. A. degree from The Cooper Union for the Advancement of Science and Art and resides in Brewster, New York.


Free Antiretrovirals Must Not Be Restricted Only to Treatment-Naive Patients

Robert Colebunders, Moses Kamya, Fred Semitala, Barbara Castelnuovo, Elly Katabira, Keith McAdam


Policy Forums

Data Cleaning: Detecting, Diagnosing, and Editing Data Abnormalities

Jan Van den Broeck, Solveig Argeseanu Cunningham, Roger Eeckels, Kobus Herbst

Research in Translation

Use of Preclinical Models to Improve Treatment of Retinoblastoma

Michael A Dyer, Carlos Rodriguez-Galindo, Matthew W Wilson

Research Articles

Latitude, Birth Date, and Allergy

Matthias Wjst, Shyamali Dharmage, Elisabeth André, Dan Norback, Chantal Raherison, Simona Villani, Jure Manfreda, Jordi Sunyer, Deborah Jarvis, Peter Burney, Cecilie Svanes

Impaired Cross-Modal Inhibition in Alzheimer Disease

Alexander Drzezga, Timo Grimmer, Martin Peller, Marc Wermke, Hartwig Siebner, Josef P Rauschecker, Markus Schwaiger, Alexander Kurz

A C1173T Dimorphism in the VKORC1 Gene Determines Coumarin Sensitivity and Bleeding Risk

Pieter H Reitsma, Jeroen F. van der Heijden, Angelique P Groot, Frits R Rosendaal, Harry R Büller

Increased Expression in Dorsolateral Prefrontal Cortex of CAPON in Schizophrenia and Bipolar Disorder

Bin Xu, Naomi Wratten, Erik I Charych, Steven Buyske, Bonnie L Firestein, Linda M Brzustowicz

Vaccination with Recombinant Aspartic Hemoglobinase Reduces Parasite Load and Blood Loss after Hookworm Infection in Dogs

Alex Loukas, Jeffrey M Bethony, Susana Mendez, Ricardo T Fujiwara, Gaddam Narsa Goud, Najju Ranjit, Bin Zhan, Karen Jones, Maria Elena Bottazzi, Peter J Hotez

Effects of ADMA upon Gene Expression: An Insight into the Pathophysiological Significance of Raised Plasma ADMA

Caroline L Smith, Shelagh Anthony, Mike Hubank, James M Leiper, Patrick Vallance



Correction: Estimation of the Total Parasite Biomass in Acute Falciparum Malaria from Plasma PfHRP2

Arjen M Dondorp, Varunee Desakorn, Wirichada Pongtavornpinyo, Duangjai Sahassananda, Kamolrat Silamut, Kesinee Chotivanich, Paul N Newton, Punnee Pitisuttithum, A. M Smithyman, Nicholas J White, Nicholas P. J Day