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Table of Contents: March 2005

COVER

Megan.

Image Credit: Amy Snyder (amys [at] exploratorium.edu)
Issue Image

I have always been drawn to photography because it allows me to step into other people's lives, to exchange stories, and to learn about a myriad of life experiences. Over the years I have photographed a number of individuals with disabilities doing everyday activities like eating a meal, tending to the garden, or taking a walk. In my work, I am interested in challenging societal assumptions about how people navigate through life. This photograph of Megan Shirle is from a series I did in collaboration with Axis Dance Company (www.axisdance.org), an innovative troupe of dancers with and without disabilities. Axis's work redefines our notion of movement and expands our concepts of dance and body image. In my photographs I aspired to capture the elegance and loveliness of composition of their artistic expression.

For the past ten years, I have been the senior photographer at the Exploratorium, an internationally renowned museum of science, art, and human perception in San Francisco, California. I have developed installations for several exhibits at the museum including the "Memory" show, the "Revealing Bodies" show, and "Mothlight." I have taught in the undergraduate precollege program at the California College of Arts and Crafts in Oakland, California, and have conducted workshops with kids on probation.

I received a BA in German from the University of Michigan-Ann Arbor, and an MFA in Photography with highest distinction from the California College of Arts and Crafts in Oakland, California.

Editorial

The PLoS Medicine Debate

Is It Always Unethical to Use a Placebo in a Clinical Trial?

Andreas Stang, Hans-Werner Hense, Karl-Heinz Jöckel, Erick H Turner, Martin R Tramèr

Essays

Neglected Diseases

Hookworm: “The Great Infection of Mankind”

Peter J Hotez, Jeff Bethony, Maria Elena Bottazzi, Simon Brooker, Paulo Buss

Health in Action

Antifibrinolytic Agents in Traumatic Haemorrhage

Tim Coats, Beverly Hunt, Ian Roberts, Haleema Shakur

Policy Forum

Protecting Children from Environmental Toxins

Bruce P Lanphear, Charles V Vorhees, David C Bellinger

Research in Translation

Case Report

Recurrent Pleural and Pericardial Effusions Due to Sarcoidosis

Sankar D Navaneethan, Sundar Venkatesh, Rakesh Shrivastava, Jagat Mehta, Robert Israel

Research Articles

A Space–Time Permutation Scan Statistic for Disease Outbreak Detection

Martin Kulldorff, Richard Heffernan, Jessica Hartman, Renato Assunção, Farzad Mostashari

Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain

William Pao, Vincent A Miller, Katerina A Politi, Gregory J Riely, Romel Somwar, Maureen F Zakowski, Mark G Kris, Harold Varmus

Serum Uric Acid and Coronary Heart Disease in 9,458 Incident Cases and 155,084 Controls: Prospective Study and Meta-Analysis

Jeremy G Wheeler, Kelsey D. M Juzwishin, Gudny Eiriksdottir, Vilmundur Gudnason, John Danesh

Noninvasive Visualization of the Activated αvβ3 Integrin in Cancer Patients by Positron Emission Tomography and [18F]Galacto-RGD

Roland Haubner, Wolfgang A Weber, Ambros J Beer, Eugenija Vabuliene, Daniel Reim, Mario Sarbia, Karl-Friedrich Becker, Michael Goebel, Rüdiger Hein, Hans-Jürgen Wester, Horst Kessler, Markus Schwaiger

T Cell Epitope Immunotherapy Induces a CD4+ T Cell Population with Regulatory Activity

Adrienne Verhoef, Clare Alexander, A. Barry Kay, Mark Larché

Correspondence

Tumor Cell Recognition Efficiency by T Cells

Daniel E Speiser, Jean-Charles Cerottini, Pedro Romero

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Tor B Stuge, Peter P Lee

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Sam Gandy, Suzana Petanceska

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Margaret Gatz

Cholesterol, Statins, and Alzheimer Disease

Alexei R Koudinov, Temirbolat T Berezov