Table of Contents: September 2015

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The REWARD/Equator Conference on Increasing value and reducing waste in biomedical research takes place on September 28-30, 2015. A co-sponsor of the Conference, PLOS Medicine is featuring two articles this month on tools to improve research design and reporting: an Essay by David Moher and Douglas Altman on "Four Proposals to Improve the Medical Research Literature", and a Guest Editorial by Cosetta Minelli and Gianluca Baio on how Value of Information analysis can reduce research waste. We also invite interested readers to check back in October for major additions to our Guidelines and Guidance series on research quality and reporting.




Moving Beyond Directly Observed Therapy for Tuberculosis

John Z. Metcalfe, Max R. O’Donnell, David R. Bangsberg

Research Articles

The Impact of Company-Level ART Provision to a Mining Workforce in South Africa: A Cost–Benefit Analysis

Gesine Meyer-Rath, Jan Pienaar, Brian Brink, Andrew van Zyl, Debbie Muirhead, Alison Grant, Gavin Churchyard, Charlotte Watts, Peter Vickerman

Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer

Pamela Maris, Arnaud Blomme, Ana Perez Palacios, Brunella Costanza, Akeila Bellahcène, Elettra Bianchi, Stephanie Gofflot, Pierre Drion, Giovanna Elvi Trombino, Emmanuel Di Valentin, Pino G. Cusumano, Sylvie Maweja, Guy Jerusalem, Philippe Delvenne, Eric Lifrange, Vincent Castronovo, Andrei Turtoi

Uptake, Accuracy, Safety, and Linkage into Care over Two Years of Promoting Annual Self-Testing for HIV in Blantyre, Malawi: A Community-Based Prospective Study

Augustine T. Choko, Peter MacPherson, Emily L. Webb, Barbara A. Willey, Helena Feasy, Rodrick Sambakunsi, Aaron Mdolo, Simon D. Makombe, Nicola Desmond, Richard Hayes, Hendramoorthy Maheswaran, Elizabeth L. Corbett

Simplified HIV Testing and Treatment in China: Analysis of Mortality Rates Before and After a Structural Intervention

Zunyou Wu, Yan Zhao, Xianmin Ge, Yurong Mao, Zhenzhu Tang, Cynthia X. Shi, Chi Chen, Yong Li, Xuejun Qiu, Guide Nong, Shanhui Huang, Shen Luo, Shaohui Wu, Wenzhen He, Mingjie Zhang, Zhiyong Shen, Xia Jin, Jian Li, Ron Brookmeyer, Roger Detels, Julio Montaner, Yu Wang

Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study

Yasmina Molero, Paul Lichtenstein, Johan Zetterqvist, Clara Hellner Gumpert, Seena Fazel

Effectiveness of Electronic Reminders to Improve Medication Adherence in Tuberculosis Patients: A Cluster-Randomised Trial

Xiaoqiu Liu, James J. Lewis, Hui Zhang, Wei Lu, Shun Zhang, Guilan Zheng, Liqiong Bai, Jun Li, Xue Li, Hongguang Chen, Mingming Liu, Rong Chen, Junying Chi, Jian Lu, Shitong Huan, Shiming Cheng, Lixia Wang, Shiwen Jiang, Daniel P. Chin, Katherine L. Fielding

Changes in Intake of Fruits and Vegetables and Weight Change in United States Men and Women Followed for Up to 24 Years: Analysis from Three Prospective Cohort Studies

Monica L. Bertoia, Kenneth J. Mukamal, Leah E. Cahill, Tao Hou, David S. Ludwig, Dariush Mozaffarian, Walter C. Willett, Frank B. Hu, Eric B. Rimm

Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal

Keira A. Cohen, Thomas Abeel, Abigail Manson McGuire, Christopher A. Desjardins, Vanisha Munsamy, Terrance P. Shea, Bruce J. Walker, Nonkqubela Bantubani, Deepak V. Almeida, Lucia Alvarado, Sinéad B. Chapman, Nomonde R. Mvelase, Eamon Y. Duffy, Michael G. Fitzgerald, Pamla Govender, Sharvari Gujja, Susanna Hamilton, Clinton Howarth, Jeffrey D. Larimer, Kashmeel Maharaj, Matthew D. Pearson, Margaret E. Priest, Qiandong Zeng, Nesri Padayatchi, Jacques Grosset, Sarah K. Young, Jennifer Wortman, Koleka P. Mlisana, Max R. O'Donnell, Bruce W. Birren, William R. Bishai, Alexander S. Pym, Ashlee M. Earl

Effectiveness of a Home-Based Counselling Strategy on Neonatal Care and Survival: A Cluster-Randomised Trial in Six Districts of Rural Southern Tanzania

Claudia Hanson, Fatuma Manzi, Elibariki Mkumbo, Kizito Shirima, Suzanne Penfold, Zelee Hill, Donat Shamba, Jennie Jaribu, Yuna Hamisi, Seyi Soremekun, Simon Cousens, Tanya Marchant, Hassan Mshinda, David Schellenberg, Marcel Tanner, Joanna Schellenberg