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Table of Contents: February 2013

COVER

Image Credit: Lirneasia at Flickr.com
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In their February editorial, the PLOS Medicine editors discuss the challenges that mobile health initiatives face in approaching their potential to transform health service delivery. The editorial highlights two systematic reviews published in the journal that address the ability of mobile health technologies to improve health care service delivery, and impact on disease management by health care consumers. It has been predicted that globally there will be more mobile phones than people by 2017, and most countries have begun to develop mobile health pilot projects or initiatives. In the editorial, the editors outline three major challenges for mobile health advocates: firstly, whether mobile health systems are able to operate with each other and with existing electronic health systems; secondly, whether systems are developed using open standards; and thirdly, how the effects of mobile health systems will be evaluated.

Editorial

Essay

Scaling Up mHealth: Where Is the Evidence?

Mark Tomlinson, Mary Jane Rotheram-Borus, Leslie Swartz, Alexander C. Tsai

Policy Forum

Who Should Pay for Global Health, and How Much?

Luis R. Carrasco, Richard Coker, Alex R. Cook

Guidelines and Guidance

Prognosis Research Strategy (PROGRESS) 2: Prognostic Factor Research

Richard D. Riley, Jill A. Hayden, Ewout W. Steyerberg, Karel G. M. Moons, Keith Abrams, Panayiotis A. Kyzas, Núria Malats, Andrew Briggs, Sara Schroter, Douglas G. Altman, Harry Hemingway , for the PROGRESS Group

Prognosis Research Strategy (PROGRESS) 3: Prognostic Model Research

Ewout W. Steyerberg, Karel G. M. Moons, Danielle A. van der Windt, Jill A. Hayden, Pablo Perel, Sara Schroter, Richard D. Riley, Harry Hemingway, Douglas G. Altman , for the PROGRESS Group

Research Articles

Prehospital Lactated Ringer's Solution Treatment and Survival in Out-of-Hospital Cardiac Arrest: A Prospective Cohort Analysis

Akihito Hagihara, Manabu Hasegawa, Takeru Abe, Yoshifumi Wakata, Takashi Nagata, Yoshihiro Nabeshima

Socioeconomic Inequalities in Lung Cancer Treatment: Systematic Review and Meta-Analysis

Lynne F. Forrest, Jean Adams, Helen Wareham, Greg Rubin, Martin White

Whole Genome Sequencing versus Traditional Genotyping for Investigation of a Mycobacterium tuberculosis Outbreak: A Longitudinal Molecular Epidemiological Study

Andreas Roetzer, Roland Diel, Thomas A. Kohl, Christian Rückert, Ulrich Nübel, Jochen Blom, Thierry Wirth, Sebastian Jaenicke, Sieglinde Schuback, Sabine Rüsch-Gerdes, Philip Supply, Jörn Kalinowski, Stefan Niemann

Global Estimates of Syphilis in Pregnancy and Associated Adverse Outcomes: Analysis of Multinational Antenatal Surveillance Data

Lori Newman, Mary Kamb, Sarah Hawkes, Gabriela Gomez, Lale Say, Armando Seuc, Nathalie Broutet

Prevalence of Age-Related Macular Degeneration in Nakuru, Kenya: A Cross-Sectional Population-Based Study

Wanjiku Mathenge, Andrew Bastawrous, Tunde Peto, Irene Leung, Allen Foster, Hannah Kuper

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts

Karani S. Vimaleswaran, Diane J. Berry, Chen Lu, Emmi Tikkanen, Stefan Pilz, Linda T. Hiraki, Jason D. Cooper, Zari Dastani, Rui Li, Denise K. Houston, Andrew R. Wood, Karl Michaëlsson, Liesbeth Vandenput, Lina Zgaga, Laura M. Yerges-Armstrong, Mark I. McCarthy, Josée Dupuis, Marika Kaakinen, Marcus E. Kleber, Karen Jameson, Nigel Arden, Olli Raitakari, Jorma Viikari, Kurt K. Lohman, Luigi Ferrucci, Håkan Melhus, Erik Ingelsson, Liisa Byberg, Lars Lind, Mattias Lorentzon, Veikko Salomaa, Harry Campbell, Malcolm Dunlop, Braxton D. Mitchell, Karl-Heinz Herzig, Anneli Pouta, Anna-Liisa Hartikainen, Elizabeth A. Streeten, Evropi Theodoratou, Antti Jula, Nicholas J. Wareham, Claes Ohlsson, Timothy M. Frayling, Stephen B. Kritchevsky, Timothy D. Spector, J. Brent Richards, Terho Lehtimäki, Willem H. Ouwehand, Peter Kraft, Cyrus Cooper, Winfried März, Chris Power, Ruth J. F. Loos, Thomas J. Wang, Marjo-Riitta Järvelin, John C. Whittaker, Aroon D. Hingorani, Elina Hyppönen , the Genetic Investigation of Anthropometric Traits (GIANT) consortium