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Table of Contents: June 2010

COVER

Maternal health: Time to deliver.

Image Credit: Pierre Holtz for UNICEF (hdptcar.net)
Issue Image

A shocking and intolerable number of women die or are disabled each year trying to give birth- more than 10 million women according to the WHO, 99% of whom are in developing countries. In an Editorial linked to a new series on maternal, neonatal, and child health in Africa, the PLoS Medicine editors argue that maternal health policies must recognize the full spectrum of women's sexual and reproductive health for improvements in maternal health to be realized. The goal of the series is to identify scientific interventions and accelerate actions that are tailored and specific to sub-Saharan Africa. Based on consultations with 60 scientists and policy makers from nine countries and using local and national data, the series updates the current status of maternal and child health in the region, reviews evidence based solutions, and identifies high-impact opportunities for reducing maternal and child mortality.

Editorial

Maternal Health: Time to Deliver

The PLoS Medicine Editors

Essays

Secondary Prevention of Suicide

Debora Ganz, M. Dolores Braquehais, Leo Sher

Health in Action

Developing ANDI: A Novel Approach to Health Product R&D in Africa

Solomon Nwaka, Tshinko B. Ilunga, Jorge Santos Da Silva, Emiliano Rial Verde, Doan Hackley, Raymond De Vré, Tom Mboya-Okeyo, Robert G. Ridley

Policy Forums

Sub-Saharan Africa's Mothers, Newborns, and Children: Where and Why Do They Die?

Mary V. Kinney, Kate J. Kerber, Robert E. Black, Barney Cohen, Francis Nkrumah, Hoosen Coovadia, Paul Michael Nampala, Joy E. Lawn , on behalf of the Science in Action: Saving the lives of Africa's mothers, newborns, and children working group

Sub-Saharan Africa's Mothers, Newborns, and Children: How Many Lives Could Be Saved with Targeted Health Interventions?

Ingrid K. Friberg, Mary V. Kinney, Joy E. Lawn, Kate J. Kerber, M. Oladoyin Odubanjo, Anne-Marie Bergh, Neff Walker, Eva Weissman, Mickey Chopra, Robert E. Black , on behalf of the Science in Action: Saving the lives of Africa's mothers, newborns, and children working group

Studies Needed to Address Public Health Challenges of the 2009 H1N1 Influenza Pandemic: Insights from Modeling

Maria D. Van Kerkhove, Tommi Asikainen, Niels G. Becker, Steven Bjorge, Jean-Claude Desenclos, Thais dos Santos, Christophe Fraser, Gabriel M. Leung, Marc Lipsitch, Ira M. Longini Jr, Emma S. McBryde, Cathy E. Roth, David K. Shay, Derek J. Smith, Jacco Wallinga, Peter J. White, Neil M. Ferguson, Steven Riley , for the WHO Informal Network for Mathematical Modelling for Pandemic Influenza H1N1 2009 (Working Group on Data Needs)

Guidelines and Guidance

Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): Extending the CONSORT Statement

Hugh MacPherson, Douglas G. Altman, Richard Hammerschlag, Li Youping, Wu Taixiang, Adrian White, David Moher , on behalf of the STRICTA Revision Group

Research Articles

The Association of Factor V Leiden and Prothrombin Gene Mutation and Placenta-Mediated Pregnancy Complications: A Systematic Review and Meta-analysis of Prospective Cohort Studies

Marc A. Rodger, Marisol T. Betancourt, Peter Clark, Pelle G. Lindqvist, Donna Dizon-Townson, Joanne Said, Uri Seligsohn, Marc Carrier, Ophira Salomon, Ian A. Greer

Estimating the Global Clinical Burden of Plasmodium falciparum Malaria in 2007

Simon I. Hay, Emelda A. Okiro, Peter W. Gething, Anand P. Patil, Andrew J. Tatem, Carlos A. Guerra, Robert W. Snow

Long-Term Biological and Behavioural Impact of an Adolescent Sexual Health Intervention in Tanzania: Follow-up Survey of the Community-Based MEMA kwa Vijana Trial

Aoife M. Doyle, David A. Ross, Kaballa Maganja, Kathy Baisley, Clemens Masesa, Aura Andreasen, Mary L. Plummer, Angela I. N. Obasi, Helen A. Weiss, Saidi Kapiga, Deborah Watson-Jones, John Changalucha, Richard J. Hayes , for the MEMA kwa Vijana Trial Study Group

Evaluating the Quality of Research into a Single Prognostic Biomarker: A Systematic Review and Meta-analysis of 83 Studies of C-Reactive Protein in Stable Coronary Artery Disease

Harry Hemingway, Peter Philipson, Ruoling Chen, Natalie K. Fitzpatrick, Jacqueline Damant, Martin Shipley, Keith R. Abrams, Santiago Moreno, Kate S. L. McAllister, Stephen Palmer, Juan Carlos Kaski, Adam D. Timmis, Aroon D. Hingorani

The Prevalence and Drug Sensitivity of Tuberculosis among Patients Dying in Hospital in KwaZulu-Natal, South Africa: A Postmortem Study

Ted Cohen, Megan Murray, Kristina Wallengren, Gonzalo G. Alvarez, Elizabeth Y. Samuel, Douglas Wilson