Table of Contents: July 2005


Escalator Guy.

Image Credit: Scott Mickelson (
Issue Image

I am extremely concerned that the information we receive through most sources of media, whether it be health issues or otherwise, is compromised by outside interests. A good example is the relationship between pharmaceutical companies and the FDA, which, in my opinion, has become dysfunctional to the point of being dangerous.

This illustration was influenced by the statement "journalists become unwitting mouthpieces for incomplete, biased, and imbalanced news and information" (see Schwitzer commentary in this issue's PLoS Medicine Debate). What immediately came to mind was the image of a mechanical-looking journalist with an open door to his head, easily accessed by an escalator. I rendered this with graphite on paper, scanned it, and then began to flesh out and color the concept in Photoshop. I used jumbled scraps of medical information to create additional texture and add another layer of storytelling.

Before returning to school to get my B.F.A. with a major in Illustration, I was a songwriter, recording artist, and record producer. It was a natural transition to the visual arts, and my Fine Art painting is still connected to my music in tone and character. There is a darker nature in both, which also comes through nicely when developing editorial illustrations.


The PLoS Medicine Debate

What Are the Roles and Responsibilities of the Media in Disseminating Health Information?

Gary Schwitzer, Ganapati Mudur, David Henry, Amanda Wilson, Merrill Goozner, Maria Simbra, Melissa Sweet, Katherine A Baverstock


Global Health Challenges: The Need for an Expanded Discourse on Bioethics

Solomon R Benatar, Abdallah S Daar, Peter A Singer

Neglected Diseases

Visceral Leishmaniasis: New Health Tools Are Needed

Asrat Hailu, Ahmed Mudawi Musa, Catherine Royce, Monique Wasunna

Health in Action

Policy Forums

Five Futures for Academic Medicine

Shally Awasthi, Jil Beardmore, Jocalyn Clark, Philip Hadridge, Hardi Madani, Ana Marusic, Gretchen Purcell, Margaret Rhoads, Karen Sliwa-Hähnle, Richard Smith, Tessa Tan-Torres Edejer, Peter Tugwell, Tim Underwood , Robyn Ward on behalf of the International Campaign to Revitalise Academic Medicine

Research in Translation

The Genetics of Schizophrenia

Patrick F Sullivan

Case Report

Research Articles

Appropriate Models for the Management of Infectious Diseases

Helen J Wearing, Pejman Rohani, Matt J Keeling

Analgesic Therapy in Postherpetic Neuralgia: A Quantitative Systematic Review

Kathleen Hempenstall, Turo J Nurmikko, Robert W Johnson, Roger P A'Hern, Andrew S.C Rice

Artemisinin versus Nonartemisinin Combination Therapy for Uncomplicated Malaria: Randomized Clinical Trials from Four Sites in Uganda

Adoke Yeka, Kristin Banek, Nathan Bakyaita, Sarah G Staedke, Moses R Kamya, Ambrose Talisuna, Fred Kironde, Samuel L Nsobya, Albert Kilian, Madeline Slater, Arthur Reingold, Philip J Rosenthal, Fred Wabwire-Mangen, Grant Dorsey

A Microchip CD4 Counting Method for HIV Monitoring in Resource-Poor Settings

William R Rodriguez, Nicolaos Christodoulides, Pierre N Floriano, Susan Graham, Sanghamitra Mohanty, Meredith Dixon, Mina Hsiang, Trevor Peter, Shabnam Zavahir, Ibou Thior, Dwight Romanovicz, Bruce Bernard, Adrian P Goodey, Bruce D Walker, John T McDevitt

Host Heterogeneous Ribonucleoprotein K (hnRNP K) as a Potential Target to Suppress Hepatitis B Virus Replication

Lisa F. P Ng, Marieta Chan, Soh-Ha Chan, Paul Chung-Pui Cheng, Eastwood Hon-Chiu Leung, Wei-Ning Chen, Ee-Chee Ren


Editors' Reply

Virginia Barbour, Barbara Cohen, Gavin Yamey

Authors' Reply: Sprinkles as a Home Fortification Strategy to Improve the Quality of Complementary Foods

Stanley H Zlotkin, Claudia Schauer, Anna Christofides, Waseem Sharieff, Mélody C Tondeur, S. M. Ziauddin Hyder

Author's Reply

Shah Ebrahim