Advertisement
Guidelines and Guidance

Guidelines and Guidance The Guidelines and Guidance section contains advice on conducting and reporting medical research.

See all article types »

The Ottawa Statement on the Ethical Design and Conduct of Cluster Randomized Trials

  • Charles Weijer mail,

    cweijer@uwo.ca

    Affiliations: Rotman Institute of Philosophy, Department of Philosophy, Western University, London, Ontario, Canada, Department of Medicine, Western University, London, Ontario, Canada, Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada

    X
  • Jeremy M. Grimshaw,

    Affiliations: Rotman Institute of Philosophy, Department of Philosophy, Western University, London, Ontario, Canada, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, Department of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Martin P. Eccles,

    Affiliation: Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom

    X
  • Andrew D. McRae,

    Affiliations: Rotman Institute of Philosophy, Department of Philosophy, Western University, London, Ontario, Canada, Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada, Division of Emergency Medicine, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada

    X
  • Angela White,

    Affiliation: Rotman Institute of Philosophy, Department of Philosophy, Western University, London, Ontario, Canada

    X
  • Jamie C. Brehaut,

    Affiliations: Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Monica Taljaard, the Ottawa Ethics of Cluster Randomized Trials Consensus Group,

    Affiliations: Rotman Institute of Philosophy, Department of Philosophy, Western University, London, Ontario, Canada, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada, Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada

    X
  • Fernando Althabe

    Membership of the Ottawa Ethics of Cluster Randomized Trials Consensus Group is provided in the Acknowledgments.

    X
  • Published: November 20, 2012
  • DOI: 10.1371/journal.pmed.1001346
  • Featured in PLOS Collections

About the Authors

Charles Weijer, Jeremy M. Grimshaw, Andrew D. McRae, Angela White, Monica Taljaard
Rotman Institute of Philosophy, Department of Philosophy, Western University, London, Ontario, Canada
Charles Weijer
Department of Medicine, Western University, London, Ontario, Canada
Charles Weijer, Andrew D. McRae
Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada
Jeremy M. Grimshaw, Jamie C. Brehaut, Monica Taljaard
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
Jeremy M. Grimshaw
Department of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Martin P. Eccles
Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom
Andrew D. McRae
Division of Emergency Medicine, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada
Jamie C. Brehaut, Monica Taljaard
Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada

Corresponding Author

Email: cweijer@uwo.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Wrote the first draft of the manuscript: CW JMG MPE ADM AW JCB MT. Contributed to the writing of the manuscript: CW JMG MPE ADM AW JCB MT. ICMJE criteria for authorship read and met: CW JMG MPE ADM AW JCB MT. Agree with manuscript results and conclusions: CW JMG MPE ADM AW JCB MT. Contributed to the conception and design of the study and secured funding: CW JMG MPE ADM JCB MT. Conducted the ethical analysis: CW JMG MPE ADM AW JCB MT.