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Research Article

Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mortality: A Large Pooled Cohort Analysis

  • Steven C. Moore mail,

    moorest@mail.nih.gov

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Alpa V. Patel,

    Affiliation: Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, United States of America

    X
  • Charles E. Matthews,

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Amy Berrington de Gonzalez,

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Yikyung Park,

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Hormuzd A. Katki,

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

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  • Martha S. Linet,

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Elisabete Weiderpass,

    Affiliations: Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, Cancer Registry of Norway, Oslo, Norway, Department of Community Medicine, Tromso, Norway, Samfundet Folkhalsan, Helsinki, Finland

    X
  • Kala Visvanathan,

    Affiliation: Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

    X
  • Kathy J. Helzlsouer,

    Affiliation: Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Michael Thun,

    Affiliation: Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, United States of America

    X
  • Susan M. Gapstur,

    Affiliation: Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, United States of America

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  • Patricia Hartge,

    Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

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  • I-Min Lee

    Affiliation: Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: November 06, 2012
  • DOI: 10.1371/journal.pmed.1001335

About the Authors

Steven C. Moore, Charles E. Matthews, Amy Berrington de Gonzalez, Yikyung Park, Hormuzd A. Katki, Martha S. Linet, Patricia Hartge
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
Alpa V. Patel, Michael Thun, Susan M. Gapstur
Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, United States of America
Elisabete Weiderpass
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
Elisabete Weiderpass
Cancer Registry of Norway, Oslo, Norway
Elisabete Weiderpass
Department of Community Medicine, Tromso, Norway
Elisabete Weiderpass
Samfundet Folkhalsan, Helsinki, Finland
Kala Visvanathan, Kathy J. Helzlsouer
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
I-Min Lee
Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Author

Email: moorest@mail.nih.gov

Competing Interests

I-Min Lee served as a consultant to Virgin HealthMiles and served on their Scientific Advisory Board (2007–2010). The authors have declared that no other competing interests exist.

Author Contributions

Conceived and designed the experiments: SCM AVP CEM ABG HAK PH IML. Performed the experiments: SCM ABG. Analyzed the data: SCM. Contributed reagents/materials/analysis tools: SCM ABG HAK. Wrote the first draft of the manuscript: SCM. Contributed to the writing of the manuscript: SCM AVP CEM ABG YP HAK PH IML. ICMJE criteria for authorship read and met: SCM AVP CEM ABG YP HAK MSL EW KV KJH MT SMG PH IML. Agree with manuscript results and conclusions: SCM AVP CEM ABG YP HAK MSL EW KV KJH MT SMG PH IML.