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Research Article

Risk Factors for Death among Children Less than 5 Years Old Hospitalized with Diarrhea in Rural Western Kenya, 2005–2007: A Cohort Study

  • Ciara E. O'Reilly mail,

    bwf1@cdc.gov

    Affiliation: Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Peter Jaron,

    Affiliation: Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya

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  • Benjamin Ochieng,

    Affiliation: Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya

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  • Amek Nyaguara,

    Affiliation: Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya

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  • Jacqueline E. Tate,

    Affiliation: Division of Viral Diseases, National Center for Immunization, and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Michele B. Parsons,

    Affiliation: Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Cheryl A. Bopp,

    Affiliation: Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Kara A. Williams,

    Affiliation: Division of Viral Diseases, National Center for Immunization, and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Jan Vinjé,

    Affiliation: Division of Viral Diseases, National Center for Immunization, and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Elizabeth Blanton,

    Affiliation: Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Kathleen A. Wannemuehler,

    Affiliation: Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • John Vulule,

    Affiliation: Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya

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  • Kayla F. Laserson,

    Affiliations: Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Robert F. Breiman,

    Affiliations: Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Daniel R. Feikin,

    Affiliations: Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Marc-Alain Widdowson,

    Affiliation: Division of Viral Diseases, National Center for Immunization, and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Eric Mintz

    Affiliation: Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Published: July 03, 2012
  • DOI: 10.1371/journal.pmed.1001256

About the Authors

Ciara E. O'Reilly, Michele B. Parsons, Cheryl A. Bopp, Elizabeth Blanton, Kathleen A. Wannemuehler, Eric Mintz
Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Peter Jaron, Benjamin Ochieng, Amek Nyaguara, Kayla F. Laserson, Robert F. Breiman, Daniel R. Feikin
Kenya Medical Research Institute/Centers for Disease Control and Prevention, Kisumu, Kenya
Jacqueline E. Tate, Kara A. Williams, Jan Vinjé, Marc-Alain Widdowson
Division of Viral Diseases, National Center for Immunization, and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
John Vulule
Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
Kayla F. Laserson, Robert F. Breiman, Daniel R. Feikin
Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Corresponding Author

Email: bwf1@cdc.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CEO'R BO AN MBP CAB JVi KAWa JVu KFL RFB DRF M-AW EM. Performed the experiments: CEO'R PJ BO AN MBP CAB KAWi JVi. Analyzed the data: CEO'R KAWa. Wrote the first draft of the manuscript: CEO'R. Contributed to the writing of the manuscript: CEO'R PJ BO AN JET MBP CAB KAWi JVi EB KAWa KFL RFB DRF M-AW EM. ICMJE criteria for authorship read and met: CEO'R PJ BO AN JET MBP CAB KAWi JVi EB KAWa JVu KFL RFB DRF M-AW EM. Agree with manuscript results and conclusions: CEO'R PJ BO AN JET MBP CAB KAWi JVi EB KAWa JVu KFL RFB DRF M-AW EM. Supervised enrollment and implementation of the study protocol: PJ BO. Supervised laboratory testing: BO MBP CAB KAWi JVi. Supervised HDSS data acquisition and interpretation of the data: AN KFL. Data acquisition and cleaning: PJ AN CEO'R JET EB. Provided the biostatistical support for the study: KAWa.