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Research Article

Six-Year Follow-Up of Impact of Co-proxamol Withdrawal in England and Wales on Prescribing and Deaths: Time-Series Study

  • Keith Hawton mail,

    keith.hawton@psych.ox.ac.uk

    Affiliation: Centre for Suicide Research, University of Oxford Department of Psychiatry, Warneford Hospital, Headington, Oxford, United Kingdom

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  • Helen Bergen,

    Affiliation: Centre for Suicide Research, University of Oxford Department of Psychiatry, Warneford Hospital, Headington, Oxford, United Kingdom

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  • Sue Simkin,

    Affiliation: Centre for Suicide Research, University of Oxford Department of Psychiatry, Warneford Hospital, Headington, Oxford, United Kingdom

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  • Claudia Wells,

    Affiliation: Office for National Statistics, Government Buildings, Newport, United Kingdom

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  • Navneet Kapur,

    Affiliation: Centre for Suicide Prevention, University of Manchester, Manchester, United Kingdom

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  • David Gunnell

    Affiliation: School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

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  • Published: May 08, 2012
  • DOI: 10.1371/journal.pmed.1001213

About the Authors

Keith Hawton, Helen Bergen, Sue Simkin
Centre for Suicide Research, University of Oxford Department of Psychiatry, Warneford Hospital, Headington, Oxford, United Kingdom
Claudia Wells
Office for National Statistics, Government Buildings, Newport, United Kingdom
Navneet Kapur
Centre for Suicide Prevention, University of Manchester, Manchester, United Kingdom
David Gunnell
School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Corresponding Author

Email: keith.hawton@psych.ox.ac.uk

Competing Interests

KH and SS were temporary advisors to the MHRA for its evaluation of the efficacy and safety profile of co-proxamol. CW works for the Office for National Statistics. All other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KH HB SS. Analyzed the data: HB. Contributed reagents/materials/analysis tools: CW. Wrote the first draft of the manuscript: KH HB. Contributed to the writing of the manuscript: KH HB SS CW NK DG. ICMJE criteria for authorship read and met: KH HB SS CW NK DG. Agree with manuscript results and conclusions: KH HB SS CW NK DG.