Advertisement
Research Article

Prevalence, Distribution, and Impact of Mild Cognitive Impairment in Latin America, China, and India: A 10/66 Population-Based Study

  • Ana Luisa Sosa equal contributor,

    equal contributor Contributed equally to this work with: Ana Luisa Sosa, Emiliano Albanese

    Affiliation: National Institute of Neurology and Neurosurgery, Autonomous National University of Mexico, Mexico City, Mexico

    X
  • Emiliano Albanese equal contributor,

    equal contributor Contributed equally to this work with: Ana Luisa Sosa, Emiliano Albanese

    Affiliation: Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, Maryland, United States of America

    X
  • Blossom C. M. Stephan,

    Affiliation: University of Cambridge, Cambridge, United Kingdom

    X
  • Michael Dewey,

    Affiliation: King's College London (Institute of Psychiatry), London, United Kingdom

    X
  • Daisy Acosta,

    Affiliation: Universidad Nacional Pedro Henriquez Ureña (UNPHU), Internal Medicine Department, Geriatric Section, Santo Domingo, Dominican Republic

    X
  • Cleusa P. Ferri,

    Affiliation: King's College London (Institute of Psychiatry), London, United Kingdom

    X
  • Mariella Guerra,

    Affiliation: Universidad Peruana Cayetano Heredia, Instituto de la Memoria y Desordenes Relacionados, Peru

    X
  • Yueqin Huang,

    Affiliation: Peking University, Institute of Mental Health, Beijing, China

    X
  • K. S. Jacob,

    Affiliation: Christian Medical College, Vellore, India

    X
  • Ivonne Z. Jiménez-Velázquez,

    Affiliation: UPR, School of Medicine, San Juan, Puerto Rico

    X
  • Juan J. Llibre Rodriguez,

    Affiliation: Medical University of Havana, Cuba

    X
  • Aquiles Salas,

    Affiliation: Medicine Department, Caracas University Hospital, Faculty of Medicine, Universidad Central de Venezuela, Caracas, Venezuela

    X
  • Joseph Williams,

    Affiliation: Institute of Community Health, Voluntary Health Services, Chennai, India

    X
  • Isaac Acosta,

    Affiliation: National Institute of Neurology and Neurosurgery, Autonomous National University of Mexico, Mexico City, Mexico

    X
  • Maribella González-Viruet,

    Affiliation: Psy D Program Carlos Albizu University, San Juan, Puerto Rico

    X
  • Milagros A. Guerra Hernandez,

    Affiliation: Policlinico Universitario 27 de Noviembre, Havana, Cuba

    X
  • Li Shuran,

    Affiliation: Peking University, Institute of Mental Health, Beijing, China

    X
  • Martin J. Prince,

    Affiliation: King's College London (Institute of Psychiatry), London, United Kingdom

    X
  • Robert Stewart mail

    r.stewart@iop.kcl.ac.uk

    Affiliation: King's College London (Institute of Psychiatry), London, United Kingdom

    X
  • Published: February 07, 2012
  • DOI: 10.1371/journal.pmed.1001170

About the Authors

Ana Luisa Sosa, Isaac Acosta
National Institute of Neurology and Neurosurgery, Autonomous National University of Mexico, Mexico City, Mexico
Emiliano Albanese
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, Maryland, United States of America
Blossom C. M. Stephan
University of Cambridge, Cambridge, United Kingdom
Michael Dewey, Cleusa P. Ferri, Martin J. Prince, Robert Stewart
King's College London (Institute of Psychiatry), London, United Kingdom
Daisy Acosta
Universidad Nacional Pedro Henriquez Ureña (UNPHU), Internal Medicine Department, Geriatric Section, Santo Domingo, Dominican Republic
Mariella Guerra
Universidad Peruana Cayetano Heredia, Instituto de la Memoria y Desordenes Relacionados, Peru
Yueqin Huang, Li Shuran
Peking University, Institute of Mental Health, Beijing, China
K. S. Jacob
Christian Medical College, Vellore, India
Ivonne Z. Jiménez-Velázquez
UPR, School of Medicine, San Juan, Puerto Rico
Juan J. Llibre Rodriguez
Medical University of Havana, Cuba
Aquiles Salas
Medicine Department, Caracas University Hospital, Faculty of Medicine, Universidad Central de Venezuela, Caracas, Venezuela
Joseph Williams
Institute of Community Health, Voluntary Health Services, Chennai, India
Maribella González-Viruet
Psy D Program Carlos Albizu University, San Juan, Puerto Rico
Milagros A. Guerra Hernandez
Policlinico Universitario 27 de Noviembre, Havana, Cuba

Corresponding Author

Email: r.stewart@iop.kcl.ac.uk

Competing Interests

The 10/66 Dementia Research Group (DRG) works closely with Alzheimer's Disease International (ADI), the non-profit federation of 77 Alzheimer associations around the world. ADI is committed to strengthening Alzheimer associations worldwide, raising awareness regarding dementia and Alzheimer's disease, and advocating for more and better services for people with dementia and their caregivers. ADI is supported in part by grants from GlaxoSmithKline, Novartis, Lundbeck, Pfizer, and Eisai. Concerning the relationship with ADI, the 10/66 Dementia Research Group is an autonomous research network administered from the Institute of Psychiatry, King's College London. Its relationship with Alzheimer's Disease International is primarily around research dissemination; the 10/66 project website is hosted on the ADI server, and the cost of developing the site was met by ADI. 10/66 routinely makes a report of ongoing projects to the ADI Council, and have provided training at ADI's Alzheimer Universities. 10/66 have not received funding from ADI to conduct research, and ADI has no influence upon or input into 10/66 published research outputs. Martin Prince (but not the 10/66 DRG per se), through IoP/ KCL has received three small grants from ADI to fund researchers based at IoP/ KCL to work on the 2009, 2010, and 2011 World Alzheimer reports (not part of the present study). MD is a paid statistical reviewer for PLoS Medicine. All other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ALS MD DA CPF MG YH KSJ IZJV JJLR AS JW MJP. Performed the experiments: ALS MD DA CPF MG YH KSJ IZJV JJLR AS JW MJP. Analyzed the data: ALS EA BCMS MD RS. Wrote the first draft of the manuscript: ALS EA RS. Contributed to the writing of the manuscript: ALS EA BCMS MD DA CPF MG YH KSJ IZJV JJLR AS JW IA MGV MAGH LS MJP RS. ICMJE criteria for authorship read and met: ALS EA BCMS MD DA CPF MG YH KSJ IZJV JJLR AS JW IA MGV MAGH LS MJP RS. Agree with manuscript results and conclusions: ALS EA BCMS MD DA CPF MG YH KSJ IZJV JJLR AS JW IA MGV MAGH LS MJP RS.