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Research Article

Life Course Trajectories of Systolic Blood Pressure Using Longitudinal Data from Eight UK Cohorts

  • Andrew K. Wills mail,

    a.wills@nshd.mrc.ac.uk

    Affiliation: Medical Research Council Unit for Lifelong Health and Ageing, University College London, London, United Kingdom

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  • Debbie A. Lawlor,

    Affiliation: Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

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  • Fiona E. Matthews,

    Affiliation: Medical Research Council Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom

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  • Avan Aihie Sayer,

    Affiliation: Medical Research Council Epidemiology Resource Centre, University of Southampton, Southampton, United Kingdom

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  • Eleni Bakra,

    Affiliation: Medical Research Council Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom

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  • Yoav Ben-Shlomo,

    Affiliation: School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

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  • Michaela Benzeval,

    Affiliation: Medical Research Council/Chief Scientist Office Social and Public Health Sciences Unit, University of Glasgow, Glasgow, United Kingdom

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  • Eric Brunner,

    Affiliation: Department of Epidemiology and Public Health, University College London, London, United Kingdom

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  • Rachel Cooper,

    Affiliation: Medical Research Council Unit for Lifelong Health and Ageing, University College London, London, United Kingdom

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  • Mika Kivimaki,

    Affiliation: Department of Epidemiology and Public Health, University College London, London, United Kingdom

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  • Diana Kuh,

    Affiliation: Medical Research Council Unit for Lifelong Health and Ageing, University College London, London, United Kingdom

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  • Graciela Muniz-Terrera,

    Affiliation: Medical Research Council Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom

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  • Rebecca Hardy

    Affiliation: Medical Research Council Unit for Lifelong Health and Ageing, University College London, London, United Kingdom

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  • Published: June 14, 2011
  • DOI: 10.1371/journal.pmed.1000440

About the Authors

Andrew K. Wills, Rachel Cooper, Diana Kuh, Rebecca Hardy
Medical Research Council Unit for Lifelong Health and Ageing, University College London, London, United Kingdom
Debbie A. Lawlor
Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
Fiona E. Matthews, Eleni Bakra, Graciela Muniz-Terrera
Medical Research Council Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom
Avan Aihie Sayer
Medical Research Council Epidemiology Resource Centre, University of Southampton, Southampton, United Kingdom
Yoav Ben-Shlomo
School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
Michaela Benzeval
Medical Research Council/Chief Scientist Office Social and Public Health Sciences Unit, University of Glasgow, Glasgow, United Kingdom
Eric Brunner, Mika Kivimaki
Department of Epidemiology and Public Health, University College London, London, United Kingdom

Corresponding Author

Email: a.wills@nshd.mrc.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ICMJE criteria for authorship read and met: AKW DAL FEM AAS EB YBS MB EB RC MK DK GMT RH. Agree with the manuscript's results and conclusions: AKW DAL FEM AAS EB YBS MB EB RC MK DK GMT RH. Designed the experiments/the study: AKW DAL MK DK RH. Analyzed the data: AKW. Collected data/did experiments for the study: AAS YBS MB EB MK. Enrolled patients: AAS YBS DK. Wrote the first draft of the paper: AKW. Contributed to the writing of the paper: AKW DAL FEM EB YBS MB EB RC MK DK GMT RH. Developed the aims and analysis plan for the study: AKW DAL RH. Co-wrote the grant that formulated the ideas of pulling together these studies: FEM. Helped maintain the data when the MRC Unit was closed down and helped in its transfer to Bristol where the study group act as custodians; helped design the protocol for the phase V follow-up; enrolled patients for phase V only; helped extract the relevant variables for this paper; helped the lead author with the use and interpretation of the relevant variables: YB-S. Principal Investigator of one of cohorts included in paper: MB. Directs the MRC National Survey of Health and Development, one of the cohorts contributing to paper, and co-authored the grant that funded the work presented in the paper: DK.