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Research Article

Intermittent Preventive Treatment of Malaria Provides Substantial Protection against Malaria in Children Already Protected by an Insecticide-Treated Bednet in Burkina Faso: A Randomised, Double-Blind, Placebo-Controlled Trial

  • Amadou T. Konaté,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Jean Baptiste Yaro,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Amidou Z. Ouédraogo,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Amidou Diarra,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Adama Gansané,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Issiaka Soulama,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • David T. Kangoyé,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Youssouf Kaboré,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Espérance Ouédraogo,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Alphonse Ouédraogo,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Alfred B. Tiono,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Issa N. Ouédraogo,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Daniel Chandramohan,

    Affiliation: London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Simon Cousens,

    Affiliation: London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Paul J. Milligan,

    Affiliation: London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Sodiomon B. Sirima,

    Affiliation: Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso

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  • Brian Greenwood,

    Affiliation: London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Diadier A. Diallo mail

    Diadier.Diallo@lshtm.ac.uk

    Affiliation: London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Published: February 01, 2011
  • DOI: 10.1371/journal.pmed.1000408

About the Authors

Amadou T. Konaté, Jean Baptiste Yaro, Amidou Z. Ouédraogo, Amidou Diarra, Adama Gansané, Issiaka Soulama, David T. Kangoyé, Youssouf Kaboré, Espérance Ouédraogo, Alphonse Ouédraogo, Alfred B. Tiono, Issa N. Ouédraogo, Sodiomon B. Sirima
Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso
Daniel Chandramohan, Simon Cousens, Paul J. Milligan, Brian Greenwood, Diadier A. Diallo
London School of Hygiene & Tropical Medicine, London, United Kingdom

Corresponding Author

Email: Diadier.Diallo@lshtm.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ICMJE criteria for authorship read and met: ATK JBY AZO AD AG IS DTK YK EO AO ABT INO DC SC PJM SBS BG DAD. Agree with the manuscript's results and conclusions: ATK JBY AZO AD AG IS DTK YK EO AO ABT INO DC SC PJM SBS BG DAD. Designed the experiments/the study: AZO EO AO ABT INO DC SC PJM SBS BG DAD. Analyzed the data: ATK AZO EO AO PJM DAD. Collected data/did experiments for the study: ATK JBY AD AG IS DTK YK EO AO INO SBS. Enrolled patients: ATK JBY AD DTK YK EO AO SBS. Wrote the first draft of the paper: ATK YK AO DAD. Contributed to the writing of the paper: ATK YK AO ABT INO DC SC PJM SBS BG DAD. Supervised field work: AG. Contributed to the design of the study; helped to write some of the computer programs for data analysis: SC.