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Research Article

Scaling Up the 2010 World Health Organization HIV Treatment Guidelines in Resource-Limited Settings: A Model-Based Analysis

  • Rochelle P. Walensky mail,

    rwalensky@partners.org

    Affiliations: Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Infectious Disease, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard University Center for AIDS Research, Harvard Institute for Global Health, Cambridge, Massachusetts, United States of America

    X
  • Robin Wood,

    Affiliation: Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa

    X
  • Andrea L. Ciaranello,

    Affiliation: Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    X
  • A. David Paltiel,

    Affiliation: Yale School of Medicine, New Haven, Connecticut, United States of America

    X
  • Sarah B. Lorenzana,

    Affiliation: Division of General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    X
  • Xavier Anglaret,

    Affiliations: INSERM Unité 897, Centre de Recherche “Epidémiologie et Biostatistique”, Bordeaux Cedex, France, Université Victor Segalen Bordeaux 2, Bordeaux, France

    X
  • Adam W. Stoler,

    Affiliation: Division of General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    X
  • Kenneth A. Freedberg,

    Affiliations: Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard University Center for AIDS Research, Harvard Institute for Global Health, Cambridge, Massachusetts, United States of America, Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • for the CEPAC-International Investigators
  • Published: December 21, 2010
  • DOI: 10.1371/journal.pmed.1000382

About the Authors

Rochelle P. Walensky, Andrea L. Ciaranello, Kenneth A. Freedberg
Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
Rochelle P. Walensky, Sarah B. Lorenzana, Adam W. Stoler, Kenneth A. Freedberg
Division of General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
Rochelle P. Walensky
Division of Infectious Disease, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
Rochelle P. Walensky, Kenneth A. Freedberg
Harvard University Center for AIDS Research, Harvard Institute for Global Health, Cambridge, Massachusetts, United States of America
Kenneth A. Freedberg
Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts, United States of America
Robin Wood
Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
A. David Paltiel
Yale School of Medicine, New Haven, Connecticut, United States of America
Xavier Anglaret
INSERM Unité 897, Centre de Recherche “Epidémiologie et Biostatistique”, Bordeaux Cedex, France
Xavier Anglaret
Université Victor Segalen Bordeaux 2, Bordeaux, France

Corresponding Author

Email: rwalensky@partners.org

Competing Interests

RPW, XA, and RW participated in the World Health Organization Guidelines 2009 revision process, including the Peer Review Panel (XA) and Review Meeting 14–16 October, 2009, Geneva, Switzerland (RPW and RW).

Author Contributions

ICMJE criteria for authorship read and met: RPW RW ALC ADP SBL XA AWS KAF. Agree with the manuscript's results and conclusions: RPW RW ALC ADP SBL XA AWS KAF. Designed the experiments/the study: RPW RW. Analyzed the data: RPW ALC SBL KAF. Collected data/did experiments for the study: RPW XA. Wrote the first draft of the paper: RPW. Contributed to the writing of the paper: RW ALC ADP SBL XA KAF. Contributed to analysis and interpretation of results: ALC ADP KAF. Developed the model: AWS.