Advertisement
Research Article

Acute Human Lethal Toxicity of Agricultural Pesticides: A Prospective Cohort Study

  • Andrew H. Dawson equal contributor mail,

    equal contributor Contributed equally to this work with: Andrew H. Dawson, Michael Eddleston

    adawson@sactrc.org

    Affiliations: South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka, School of Medicine and Public Health, University of Newcastle, Newcastle, Australia, Professorial Medicine Unit, POW Clinical School, University of New South Wales, Sydney, Australia

    X
  • Michael Eddleston equal contributor,

    equal contributor Contributed equally to this work with: Andrew H. Dawson, Michael Eddleston

    Affiliations: South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka, National Poisons Information Service - Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom, Clinical Pharmacology Unit, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom

    X
  • Lalith Senarathna,

    Affiliation: South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka

    X
  • Fahim Mohamed,

    Affiliation: South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka

    X
  • Indika Gawarammana,

    Affiliation: South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka

    X
  • Steven J. Bowe,

    Affiliation: School of Medicine and Public Health, University of Newcastle, Newcastle, Australia

    X
  • Gamini Manuweera,

    Affiliation: Office of the Pesticide Registrar, Government Department of Agriculture, Peradeniya, Sri Lanka

    X
  • Nicholas A. Buckley

    Affiliations: South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka, Professorial Medicine Unit, POW Clinical School, University of New South Wales, Sydney, Australia

    X
  • Published: October 26, 2010
  • DOI: 10.1371/journal.pmed.1000357

About the Authors

Andrew H. Dawson, Michael Eddleston, Lalith Senarathna, Fahim Mohamed, Indika Gawarammana, Nicholas A. Buckley
South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka
Andrew H. Dawson, Steven J. Bowe
School of Medicine and Public Health, University of Newcastle, Newcastle, Australia
Andrew H. Dawson, Nicholas A. Buckley
Professorial Medicine Unit, POW Clinical School, University of New South Wales, Sydney, Australia
Michael Eddleston
National Poisons Information Service - Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
Michael Eddleston
Clinical Pharmacology Unit, Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom
Gamini Manuweera
Office of the Pesticide Registrar, Government Department of Agriculture, Peradeniya, Sri Lanka

Corresponding Author

Email: adawson@sactrc.org

Competing Interests

ME has received financial support to attend a scientific meeting of a study funded by Syngenta. NAB and AHD have received travel expenses from Syngenta (a manufacturer of paraquat and some other pesticides) to attend meetings of a scientific advisory group in relation to studies of new paraquat formulations.

Author Contributions

ICMJE criteria for authorship read and met: AHD ME LS FM IG SJB GM NAB. Agree with the manuscript's results and conclusions: AHD ME LS FM IG SJB GM NAB. Designed the experiments/the study: AHD ME LS IG NAB. Analyzed the data: AHD FM SJB NAB. Collected data/did experiments for the study: AHD ME LS FM IG NAB. Enrolled patients: ME LS FM IG. Wrote the first draft of the paper: AHD. Contributed to the writing of the paper: AHD ME LS FM IG GM NAB.