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Research Article

Community Case Management of Fever Due to Malaria and Pneumonia in Children Under Five in Zambia: A Cluster Randomized Controlled Trial

  • Kojo Yeboah-Antwi mail,

    kyantwi@bu.edu

    Affiliation: Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America

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  • Portipher Pilingana,

    Affiliation: Chikankata Mission Hospital, Chikankata, Southern Province, Zambia

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  • William B. Macleod,

    Affiliation: Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America

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  • Katherine Semrau,

    Affiliation: Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America

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  • Kazungu Siazeele,

    Affiliation: Chikankata Mission Hospital, Chikankata, Southern Province, Zambia

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  • Penelope Kalesha,

    Affiliation: Child Health Unit, Ministry of Health, Lusaka, Zambia

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  • Busiku Hamainza,

    Affiliation: National Malaria Control Center, Ministry of Health, Lusaka, Zambia

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  • Phil Seidenberg,

    Affiliations: Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America, Center for International Health and Development-Zambia, Lusaka, Zambia

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  • Arthur Mazimba,

    Affiliation: Center for International Health and Development-Zambia, Lusaka, Zambia

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  • Lora Sabin,

    Affiliation: Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America

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  • Karen Kamholz,

    Affiliation: Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts, United States of America

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  • Donald M. Thea,

    Affiliation: Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America

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  • Davidson H. Hamer

    Affiliations: Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America, Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

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  • Published: September 21, 2010
  • DOI: 10.1371/journal.pmed.1000340

About the Authors

Kojo Yeboah-Antwi, William B. Macleod, Katherine Semrau, Phil Seidenberg, Lora Sabin, Donald M. Thea, Davidson H. Hamer
Center for Global Health and Development, Boston University School of Public Health, Boston, Massachusetts, United States of America
Portipher Pilingana, Kazungu Siazeele
Chikankata Mission Hospital, Chikankata, Southern Province, Zambia
Penelope Kalesha
Child Health Unit, Ministry of Health, Lusaka, Zambia
Busiku Hamainza
National Malaria Control Center, Ministry of Health, Lusaka, Zambia
Phil Seidenberg, Arthur Mazimba
Center for International Health and Development-Zambia, Lusaka, Zambia
Karen Kamholz
Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts, United States of America
Davidson H. Hamer
Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

Corresponding Author

Email: kyantwi@bu.edu

Competing Interests

DHH owns shares in Inverness Medical Innovations, Inc., a company that makes diagnostic products including a malaria rapid diagnostic test. However, the rapid diagnostic tests we used in this study were not produced by Inverness Medical innovations, Inc.

Author Contributions

ICMJE criteria for authorship read and met: KYA PP WBM KS KS PK BH PS AM LS KK DMT DHH. Agree with the manuscript's results and conclusions: KYA PP WBM KS KS PK BH PS AM LS KK DMT DHH. Designed the experiments/the study: KYA PP LS DMT DHH. Analyzed the data: KYA PP WBM KS PK BH PS DHH. Collected data/did experiments for the study: KYA PP KS. Enrolled patients: PP KS. Wrote the first draft of the paper: KYA PK DHH. Contributed to the writing of the paper: KYA PP WBM KS KS PK BH PS LS KK DMT DHH. Responsible for day to day field activities: PP. Contributed to editing the manuscript: AM.