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Research Article

Economic Appraisal of Ontario's Universal Influenza Immunization Program: A Cost-Utility Analysis

  • Beate Sander mail,

    bsander@uhnres.utoronto.ca

    Affiliations: Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada, Division of Clinical Decision-Making and Health Care Research, University Health Network, Toronto, Canada, Toronto Health Economics and Technology Assessment Collaborative, Toronto, Canada

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  • Jeffrey C. Kwong,

    Affiliations: Institute for Clinical Evaluative Sciences, Toronto, Canada, Department of Family and Community Medicine, University of Toronto, Toronto, Canada, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada

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  • Chris T. Bauch,

    Affiliations: Toronto Health Economics and Technology Assessment Collaborative, Toronto, Canada, Department of Mathematics and Statistics, University of Guelph, Guelph, Canada

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  • Andreas Maetzel,

    Affiliations: Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada, Amgen (Europe) GmbH, Zug, Switzerland

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  • Allison McGeer,

    Affiliation: Division of Infectious Diseases, University Health Network, Toronto, Canada

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  • Janet M. Raboud,

    Affiliations: Dalla Lana School of Public Health, University of Toronto, Toronto, Canada, Division of Infectious Diseases, University Health Network, Toronto, Canada

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  • Murray Krahn

    Affiliations: Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada, Division of Clinical Decision-Making and Health Care Research, University Health Network, Toronto, Canada, Toronto Health Economics and Technology Assessment Collaborative, Toronto, Canada, Faculty of Pharmacy, University of Toronto, Toronto, Canada, Department of Medicine, University of Toronto, Toronto, Canada

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  • Published: April 06, 2010
  • DOI: 10.1371/journal.pmed.1000256

About the Authors

Beate Sander, Andreas Maetzel, Murray Krahn
Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada
Beate Sander, Murray Krahn
Division of Clinical Decision-Making and Health Care Research, University Health Network, Toronto, Canada
Beate Sander, Chris T. Bauch, Murray Krahn
Toronto Health Economics and Technology Assessment Collaborative, Toronto, Canada
Jeffrey C. Kwong
Institute for Clinical Evaluative Sciences, Toronto, Canada
Jeffrey C. Kwong
Department of Family and Community Medicine, University of Toronto, Toronto, Canada
Jeffrey C. Kwong, Janet M. Raboud
Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
Chris T. Bauch
Department of Mathematics and Statistics, University of Guelph, Guelph, Canada
Andreas Maetzel
Amgen (Europe) GmbH, Zug, Switzerland
Allison McGeer, Janet M. Raboud
Division of Infectious Diseases, University Health Network, Toronto, Canada
Murray Krahn
Faculty of Pharmacy, University of Toronto, Toronto, Canada
Murray Krahn
Department of Medicine, University of Toronto, Toronto, Canada

Corresponding Author

Email: bsander@uhnres.utoronto.ca

Competing Interests

BS has served as consultant to F. Hoffmann La-Roche for economic evaluations of Tamiflu (unrestricted funding). BS has received travel grants and honoraria for speaking at meetings on pandemic influenza mitigation strategies from F. Hoffmann La-Roche.

Author Contributions

ICMJE criteria for authorship read and met: BS JCK CTB AM AM JMR MDK. Agree with the manuscript's results and conclusions: BS JCK CTB AM AM JMR MDK. Designed the experiments/the study: BS CTB AM AM JMR MDK. Analyzed the data: BS. Collected data/did experiments for the study: BS JCK. Wrote the first draft of the paper: BS. Contributed to the writing of the paper: JCK CTB AM AM JMR MDK.