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A Compendium of Potential Biomarkers of Pancreatic Cancer

  • H. C. Harsha,

    Affiliations: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India, Manipal University, Manipal, Karnataka, India, McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Kumaran Kandasamy,

    Affiliations: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India, McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Prathibha Ranganathan,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Sandhya Rani,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Subhashri Ramabadran,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Sashikanth Gollapudi,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Lavanya Balakrishnan,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Sutopa B. Dwivedi,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Deepthi Telikicherla,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Lakshmi Dhevi N. Selvan,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Renu Goel,

    Affiliation: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India

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  • Suresh Mathivanan,

    Affiliations: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India, McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Arivusudar Marimuthu,

    Affiliations: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India, Manipal University, Manipal, Karnataka, India, McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Manoj Kashyap,

    Affiliations: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India, McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Robert F. Vizza,

    Affiliation: The Lustgarten Foundation for Pancreatic Cancer Research, Bethpage, New York, United States of America

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  • Robert J. Mayer,

    Affiliation: Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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  • James A. DeCaprio,

    Affiliation: Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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  • Sudhir Srivastava,

    Affiliation: Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Samir M. Hanash,

    Affiliation: Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Ralph H. Hruban,

    Affiliation: Departments of Pathology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institution, Baltimore, Maryland, United States of America

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  • Akhilesh Pandey mail

    pandey@jhmi.edu

    Affiliations: Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India, McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, United States of America, Departments of Pathology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institution, Baltimore, Maryland, United States of America

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  • Published: April 07, 2009
  • DOI: 10.1371/journal.pmed.1000046

About the Authors

H. C. Harsha, Kumaran Kandasamy, Prathibha Ranganathan, Sandhya Rani, Subhashri Ramabadran, Sashikanth Gollapudi, Lavanya Balakrishnan, Sutopa B. Dwivedi, Deepthi Telikicherla, Lakshmi Dhevi N. Selvan, Renu Goel, Suresh Mathivanan, Arivusudar Marimuthu, Manoj Kashyap, Akhilesh Pandey
Institute of Bioinformatics, International Technology Park, Bangalore, Karnataka, India
H. C. Harsha, Arivusudar Marimuthu
Manipal University, Manipal, Karnataka, India
H. C. Harsha, Kumaran Kandasamy, Suresh Mathivanan, Arivusudar Marimuthu, Manoj Kashyap, Akhilesh Pandey
McKusick-Nathans Institute of Genetic Medicine and Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, United States of America
Robert F. Vizza
The Lustgarten Foundation for Pancreatic Cancer Research, Bethpage, New York, United States of America
Robert J. Mayer, James A. DeCaprio
Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
Sudhir Srivastava
Cancer Biomarkers Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Samir M. Hanash
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Ralph H. Hruban, Akhilesh Pandey
Departments of Pathology and Oncology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institution, Baltimore, Maryland, United States of America

Corresponding Author

Email: pandey@jhmi.edu

Competing Interests

RHH has the potential to receive milestone payments and royalties from Anza Therapeutics as a result of the mesothelin invention.

Author Contributions

ICMJE criteria for authorship read and met: H Harsha K Kandasamy P Ranganathan S Rani S Ramabadran S Gollapudi L Balakrishnan S Dwivedi D Telikicherla L Selvan R Goel S Mathivanan A Marimuthu M Kashyap R Vizza R Mayer J DeCaprio S Srivastava S Hanash R Hruban A Pandey. Agree with the manuscript's results and conclusions: H Harsha K Kandasamy P Ranganathan S Rani S Ramabadran S Gollapudi L Balakrishnan S Dwivedi D Telikicherla L Selvan R Goel S Mathivanan A Marimuthu M Kashyap R Vizza R Mayer J DeCaprio S Srivastava S Hanash R Hruban A Pandey. Designed the experiments/the study: H Harsha R Vizza S Srivastava R Hruban A Pandey. Analyzed the data: H Harsha J DeCaprio A Pandey. Collected data/did experiments for the study: H Harsha K Kandasamy P Ranganathan S Rani S Ramabadran S Gollapudi L Balakrishnan S Dwivedi D Telikicherla L Selvan R Goel S Mathivanan A Marimuthu M Kashyap A Pandey. Wrote the first draft of the paper: H Harsha A Pandey. Contributed to the writing of the paper: H Harsha S Hanash R Hruban A Pandey. Reviewed a draft of the paper: R Mayer. Critically revised the paper for important intellectual content: J DeCaprio.