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Research Article

Pharmacy Refill Adherence Compared with CD4 Count Changes for Monitoring HIV-Infected Adults on Antiretroviral Therapy

  • Gregory P Bisson mail,

    To whom correspondence should be addressed. E-mail: gregbisson@mac.com (GB), jnachega@jhsph.edu (JBN)

    Affiliations: Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Robert Gross,

    Affiliations: Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Scarlett Bellamy,

    Affiliation: Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Jesse Chittams,

    Affiliation: Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Michael Hislop,

    Affiliation: Aid for AIDS Disease Management Programme, Cape Town, South Africa

    X
  • Leon Regensberg,

    Affiliation: Aid for AIDS Disease Management Programme, Cape Town, South Africa

    X
  • Ian Frank,

    Affiliation: Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Gary Maartens,

    Affiliation: Department of Medicine, Division of Clinical Pharmacology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa

    X
  • Jean B Nachega mail

    To whom correspondence should be addressed. E-mail: gregbisson@mac.com (GB), jnachega@jhsph.edu (JBN)

    Affiliations: Department of Medicine, Division of Clinical Pharmacology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa, Center for Infectious Diseases, Faculty of Health Sciences, Stellenbosch University, Tygerberg Campus, Cape Town, South Africa, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Published: May 20, 2008
  • DOI: 10.1371/journal.pmed.0050109

About the Authors

Gregory P Bisson, Robert Gross, Ian Frank
Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
Gregory P Bisson, Robert Gross, Scarlett Bellamy, Jesse Chittams
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
Michael Hislop, Leon Regensberg
Aid for AIDS Disease Management Programme, Cape Town, South Africa
Gary Maartens, Jean B Nachega
Department of Medicine, Division of Clinical Pharmacology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa
Jean B Nachega
Center for Infectious Diseases, Faculty of Health Sciences, Stellenbosch University, Tygerberg Campus, Cape Town, South Africa
Jean B Nachega
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

GPB, RG, IF, GM, and JBN designed the experiments and the study. MH collected data for the study. MH was responsible for data collection, preparation, extraction, and reporting for the Aid for AIDS Disease Management Programme. GPB, SB, and JC performed the statistical analyses. GPB wrote the first draft of the paper. All authors contributed to the analysis and interpretation of the data summarized in the manuscript, and all authors contributed to revising and finalizing the paper.