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Research Article

Episodic Sexual Transmission of HIV Revealed by Molecular Phylodynamics

  • Fraser Lewis equal contributor,

    equal contributor Contributed equally to this work with: Fraser Lewis, Gareth J Hughes

    Affiliation: Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland

    ¤ Current address: Veterinary Epidemiology Research Unit, SAC (Scottish Agricultural College), Inverness, Scotland

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  • Gareth J Hughes equal contributor,

    equal contributor Contributed equally to this work with: Fraser Lewis, Gareth J Hughes

    Affiliation: Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland

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  • Andrew Rambaut,

    Affiliation: Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland

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  • Anton Pozniak,

    Affiliation: Chelsea and Westminster Hospital, London, United Kingdom

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  • Andrew J. Leigh Brown mail

    To whom correspondence should be addressed. E-mail: A.Leigh-Brown@ed.ac.uk

    Affiliation: Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland

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  • Published: March 18, 2008
  • DOI: 10.1371/journal.pmed.0050050

About the Authors

Fraser Lewis, Gareth J Hughes, Andrew Rambaut, Andrew J. Leigh Brown
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland
Anton Pozniak
Chelsea and Westminster Hospital, London, United Kingdom

Corresponding Author

Email: A.Leigh-Brown@ed.ac.uk

Competing Interests

ALP reports receiving consulting and lecture fees from Bristol-Myers Squibb, Gilead Sciences, and GlaxoSmithKline. The other authors declare that they have no competing interests.

Author Contributions

FL and AJLB designed the study, and FL performed preliminary analyses. GJH analyzed the data and prepared the results for publication. AR developed the BEAST software and provided advice and assistance for data analysis. ALP recruited study subjects and supervised clinical care. All authors contributed to writing the paper.