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Research Article

Antiretroviral Treatment and Prevention of Peripartum and Postnatal HIV Transmission in West Africa: Evaluation of a Two-Tiered Approach

  • Besigin Tonwe-Gold equal contributor,

    equal contributor Contributed equally to this work with: Besigin Tonwe-Gold, Didier K Ekouevi

    Affiliations: MTCT-Plus Programme, ACONDA, Abidjan, Côte d'Ivoire, Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux, France, INSERM Unité 593, Bordeaux, France

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  • Didier K Ekouevi equal contributor,

    equal contributor Contributed equally to this work with: Besigin Tonwe-Gold, Didier K Ekouevi

    Affiliations: MTCT-Plus Programme, ACONDA, Abidjan, Côte d'Ivoire, Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux, France, INSERM Unité 593, Bordeaux, France

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  • Ida Viho,

    Affiliations: MTCT-Plus Programme, ACONDA, Abidjan, Côte d'Ivoire, ANRS 1201/1202, Ditrame Plus Project, PACCI Collaboration, Abidjan, Côte d'Ivoire

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  • Clarisse Amani-Bosse,

    Affiliations: MTCT-Plus Programme, ACONDA, Abidjan, Côte d'Ivoire, ANRS 1201/1202, Ditrame Plus Project, PACCI Collaboration, Abidjan, Côte d'Ivoire

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  • Siaka Toure,

    Affiliation: MTCT-Plus Programme, ACONDA, Abidjan, Côte d'Ivoire

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  • Patrick A Coffie,

    Affiliations: Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux, France, INSERM Unité 593, Bordeaux, France

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  • François Rouet,

    Affiliation: CeDReS Laboratory, Centre Hospitalier Universitaire Treichville, Abidjan, Côte d'Ivoire

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  • Renaud Becquet,

    Affiliations: Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux, France, INSERM Unité 593, Bordeaux, France

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  • Valériane Leroy,

    Affiliations: Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux, France, INSERM Unité 593, Bordeaux, France

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  • Wafaa M El-Sadr,

    Affiliation: MTCT-Plus Initiative, International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, New York, United States of America

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  • Elaine J Abrams,

    Affiliation: MTCT-Plus Initiative, International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, New York, United States of America

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  • François Dabis mail

    To whom correspondence should be addressed. E-mail: francois.dabis@isped.u-bordeaux2.fr

    Affiliations: Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux, France, INSERM Unité 593, Bordeaux, France

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  • Published: August 21, 2007
  • DOI: 10.1371/journal.pmed.0040257

About the Authors

Besigin Tonwe-Gold, Didier K Ekouevi, Ida Viho, Clarisse Amani-Bosse, Siaka Toure
MTCT-Plus Programme, ACONDA, Abidjan, Côte d'Ivoire
Besigin Tonwe-Gold, Didier K Ekouevi, Patrick A Coffie, Renaud Becquet, Valériane Leroy, François Dabis
Institut de Santé Publique, Epidémiologie et Développement, Université Victor Segalen, Bordeaux, France
Besigin Tonwe-Gold, Didier K Ekouevi, Patrick A Coffie, Renaud Becquet, Valériane Leroy, François Dabis
INSERM Unité 593, Bordeaux, France
Ida Viho, Clarisse Amani-Bosse
ANRS 1201/1202, Ditrame Plus Project, PACCI Collaboration, Abidjan, Côte d'Ivoire
François Rouet
CeDReS Laboratory, Centre Hospitalier Universitaire Treichville, Abidjan, Côte d'Ivoire
Wafaa M El-Sadr, Elaine J Abrams
MTCT-Plus Initiative, International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, New York, United States of America

Corresponding Author

Email: francois.dabis@isped.u-bordeaux2.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

BTG, DKE, WMES, and FD designed the study. BTG, DKE, PAC, VL, and EJA analyzed the data. BTG, IV, CAB, and ST enrolled patients. BTG, DKE, CAB, PAC, RB, VL, WMES, EJA, and FD contributed to writing the paper. BTG collected data/performed experiments. IV monitored the study, supervised the study team, and contributed to the event documentation committee. CAB was responsible for the coordination of the MTCT program in Abidjan. FR was responsible for all biological activities carried out in the CeDReS laboratory (Abidjan, Côte d'Ivoire).