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Research Article

Optimizing the Dose of Pre-Pandemic Influenza Vaccines to Reduce the Infection Attack Rate

  • Steven Riley equal contributor mail,

    equal contributor Contributed equally to this work with: Steven Riley, Joseph T Wu

    To whom correspondence should be addressed. E-mail: steven.riley@hku.hk

    Affiliation: Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

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  • Joseph T Wu equal contributor,

    equal contributor Contributed equally to this work with: Steven Riley, Joseph T Wu

    Affiliation: Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

    X
  • Gabriel M Leung

    Affiliation: Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

    X
  • Published: June 19, 2007
  • DOI: 10.1371/journal.pmed.0040218

About the Authors

Steven Riley, Joseph T Wu, Gabriel M Leung
Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

Corresponding Author

Email: steven.riley@hku.hk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

All authors contributed to study design, interpretation of findings, and writing the paper. SR and JTW analysed the data. SR wrote the first draft of the manuscript and constructed an independent model to validate key findings. JTW designed and implemented the main mathematical model and identified previously published data sets in the literature.