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Research Article

Factors Associated with Findings of Published Trials of Drug–Drug Comparisons: Why Some Statins Appear More Efficacious than Others

  • Lisa Bero mail,

    To whom correspondence should be addressed. E-mail: berol@pharmacy.ucsf.edu

    Affiliation: Clinical Pharmacy and Health Policy, University of California, San Francisco, California, United States of America

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  • Fieke Oostvogel,

    Affiliation: Department of Mathematics, University of Leiden, The Netherlands

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  • Peter Bacchetti,

    Affiliation: Department of Epidemiology and Biostatistics, University of California, San Francisco, California, United States of America

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  • Kirby Lee

    Affiliation: Department of Clinical Pharmacy, University of California, San Francisco, California, United States of America

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  • Published: June 05, 2007
  • DOI: 10.1371/journal.pmed.0040184

About the Authors

Lisa Bero
Clinical Pharmacy and Health Policy, University of California, San Francisco, California, United States of America
Fieke Oostvogel
Department of Mathematics, University of Leiden, The Netherlands
Peter Bacchetti
Department of Epidemiology and Biostatistics, University of California, San Francisco, California, United States of America
Kirby Lee
Department of Clinical Pharmacy, University of California, San Francisco, California, United States of America

Corresponding Author

Email: berol@pharmacy.ucsf.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

LB designed the study, analyzed data, and drafted the manuscript. FO collected data. KL advised on study design. LB, FO, and KL coded data. FO, PB, and KL advised on analysis. PB conducted analysis. FO, PB, and KL revised the paper.