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Research Article

Earlier Mother's Age at Menarche Predicts Rapid Infancy Growth and Childhood Obesity

  • Ken K Ong mail,

    To whom correspondence should be addressed. E-mail: ken.ong@mrc-epid.cam.ac.uk

    Affiliations: Medical Research Council Epidemiology Unit, Cambridge, United Kingdom, Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom

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  • Kate Northstone,

    Affiliation: Department of Social Medicine, University of Bristol, United Kingdom

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  • Jonathan CK Wells,

    Affiliation: Childhood Nutrition Research Centre, Institute of Child Health, London, United Kingdom

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  • Carol Rubin,

    Affiliation: National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, United States of America

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  • Andy R Ness,

    Affiliation: Department of Social Medicine, University of Bristol, United Kingdom

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  • Jean Golding,

    Affiliation: Department of Community Based Medicine, University of Bristol, United Kingdom

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  • David B Dunger

    Affiliation: Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom

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  • Published: April 24, 2007
  • DOI: 10.1371/journal.pmed.0040132

About the Authors

Ken K Ong
Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
Ken K Ong, David B Dunger
Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom
Kate Northstone, Andy R Ness
Department of Social Medicine, University of Bristol, United Kingdom
Jonathan CK Wells
Childhood Nutrition Research Centre, Institute of Child Health, London, United Kingdom
Carol Rubin
National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, United States of America
Jean Golding
Department of Community Based Medicine, University of Bristol, United Kingdom

Corresponding Author

Email: ken.ong@mrc-epid.cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KKO, CR and DBD contributed to the original hypothesis. KKO, CR, ARN, JG and DBD contributed to the study design. ARN and JG oversaw the fieldwork and acquisition of the data. KKO and KN performed data management and statistical analyses. All authors contributed to interpretation of the data and writing the paper.