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Research Article

A Prospective Study of Plasma Vitamin D Metabolites, Vitamin D Receptor Polymorphisms, and Prostate Cancer

  • Haojie Li mail,

    To whom correspondence should be addressed. E-mail: haojie.li@channing.havard.edu

    Affiliation: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Meir J Stampfer,

    Affiliations: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America, Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Massachusetts Veterans Epidemiology Research and Information Center, Veterans Administration Boston Healthcare System, Massachusetts, United States of America

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  • J. Bruce W Hollis,

    Affiliation: Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Lorelei A Mucci,

    Affiliation: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • J. Michael Gaziano,

    Affiliations: Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Massachusetts Veterans Epidemiology Research and Information Center, Veterans Administration Boston Healthcare System, Massachusetts, United States of America

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  • David Hunter,

    Affiliations: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

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  • Edward L Giovannucci,

    Affiliations: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

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  • Jing Ma

    Affiliation: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: March 20, 2007
  • DOI: 10.1371/journal.pmed.0040103

About the Authors

Haojie Li, Meir J Stampfer, Lorelei A Mucci, David Hunter, Edward L Giovannucci, Jing Ma
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Meir J Stampfer, David Hunter, Edward L Giovannucci
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
Meir J Stampfer, David Hunter, Edward L Giovannucci
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
Meir J Stampfer, J. Michael Gaziano
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Meir J Stampfer, J. Michael Gaziano
Massachusetts Veterans Epidemiology Research and Information Center, Veterans Administration Boston Healthcare System, Massachusetts, United States of America
J. Bruce W Hollis
Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America

Corresponding Author

Email: haojie.li@channing.havard.edu

Competing Interests

BH is a consultant for DiaSorin Corp for the assay of 25(OH)D.

Author Contributions

MJS, ELG, and JM conceived and wrote the initial study proposal and contributed substantially to conception and design of the research study. BWH, JMG, and DH made substantial contributions to acquisition of data. HL performed data analysis and drafted the manuscript. MJS, ELG, LAM, and JM participated in results interpretation and editing of the manuscript. All authors approved the final version of the manuscript.