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Research Article

Reporting Methods of Blinding in Randomized Trials Assessing Nonpharmacological Treatments

  • Isabelle Boutron mail,

    To whom correspondence should be addressed. E-mail: isabelle.boutron@bch.ap-hop-paris.fr

    Affiliations: INSERM, U738, Paris, France, Université Paris 7, UFR de Médecine, Paris, France, AP-HP, Hôpital Bichat, Département d'Epidémiologie, Biostastique et Recherche Clinique, Paris, France

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  • Lydia Guittet,

    Affiliations: INSERM, U738, Paris, France, Université Paris 7, UFR de Médecine, Paris, France, AP-HP, Hôpital Bichat, Département d'Epidémiologie, Biostastique et Recherche Clinique, Paris, France

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  • Candice Estellat,

    Affiliations: INSERM, U738, Paris, France, Université Paris 7, UFR de Médecine, Paris, France, AP-HP, Hôpital Bichat, Département d'Epidémiologie, Biostastique et Recherche Clinique, Paris, France

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  • David Moher,

    Affiliations: Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada, Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada

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  • Asbjørn Hróbjartsson,

    Affiliation: Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark

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  • Philippe Ravaud

    Affiliations: INSERM, U738, Paris, France, Université Paris 7, UFR de Médecine, Paris, France, AP-HP, Hôpital Bichat, Département d'Epidémiologie, Biostastique et Recherche Clinique, Paris, France

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  • Published: February 20, 2007
  • DOI: 10.1371/journal.pmed.0040061

About the Authors

Isabelle Boutron, Lydia Guittet, Candice Estellat, Philippe Ravaud
INSERM, U738, Paris, France
Isabelle Boutron, Lydia Guittet, Candice Estellat, Philippe Ravaud
Université Paris 7, UFR de Médecine, Paris, France
Isabelle Boutron, Lydia Guittet, Candice Estellat, Philippe Ravaud
AP-HP, Hôpital Bichat, Département d'Epidémiologie, Biostastique et Recherche Clinique, Paris, France
David Moher
Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada
David Moher
Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada
Asbjørn Hróbjartsson
Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark

Corresponding Author

Email: isabelle.boutron@bch.ap-hop-paris.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

IB, AH, and PR designed the study. IB, LG, and CE acquired the data. IB, LG, CE, DM, AH, and PR analyzed and interpreted the data. IB drafted the article. LG, CE, DM, AH, and PR critically revised the article for important intellectual content. IB, LG, CE, DM, AH, and PR gave final approval of the version to be published.