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Research Article

MHC Haplotype Matching for Unrelated Hematopoietic Cell Transplantation

  • Effie W Petersdorf mail,

    To whom correspondence should be addressed. E-mail: epetersd@fhcrc.org

    Affiliations: Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, The University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Mari Malkki,

    Affiliation: Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Ted A Gooley,

    Affiliations: Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, The Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

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  • Paul J Martin,

    Affiliations: Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, The University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Zhen Guo

    Affiliation: Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Published: January 30, 2007
  • DOI: 10.1371/journal.pmed.0040008

About the Authors

Effie W Petersdorf, Mari Malkki, Ted A Gooley, Paul J Martin, Zhen Guo
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Effie W Petersdorf, Paul J Martin
The University of Washington School of Medicine, Seattle, Washington, United States of America
Ted A Gooley
The Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

Corresponding Author

Email: epetersd@fhcrc.org

Competing Interests

EWP and ZG have applied for a US non-provisional 111(a) patent for the haplotyping method, serial number 10/843,985. The remaining authors have no conflict of interest.

Author Contributions

EWP contributed the study hypothesis and study design. ZG developed and carried out the haplotyping protocol, and MM managed the laboratory database. EWP, MM, and ZG analyzed haplotyping data, and PJM assisted in the analysis of GVHD. TAG performed the statistical analysis. All authors contributed to the preparation of the manuscript.