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Research Article

Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism

  • Gürkan Kaya mail,

    To whom correspondence should be addressed. E-mail: gkaya@hcuge.ch

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Christian Tran,

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Olivier Sorg,

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Raymonde Hotz,

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Denise Grand,

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Pierre Carraux,

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Liliane Didierjean,

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Ivan Stamenkovic,

    Affiliation: Institute of Pathology, University of Lausanne, Lausanne, Switzerland

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  • Jean-Hilaire Saurat

    Affiliation: Department of Dermatology, University of Geneva, Geneva, Switzerland

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  • Published: December 19, 2006
  • DOI: 10.1371/journal.pmed.0030493

About the Authors

Gürkan Kaya, Christian Tran, Olivier Sorg, Raymonde Hotz, Denise Grand, Pierre Carraux, Liliane Didierjean, Jean-Hilaire Saurat
Department of Dermatology, University of Geneva, Geneva, Switzerland
Ivan Stamenkovic
Institute of Pathology, University of Lausanne, Lausanne, Switzerland

Corresponding Author

Email: gkaya@hcuge.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

GK, IS, and JHS designed the study. GK, CT, OS, LD, IS, and JHS analyzed the data. GK and JHS enrolled patients. GK, CT, OS, LD, IS, and JHS contributed to writing the paper. GK, RH, DG, and PC collected data or did experiments for the study.