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Research Article

Emergence of Drug Resistance Is Associated with an Increased Risk of Death among Patients First Starting HAART

  • Robert S Hogg mail,

    To whom correspondence should be addressed. E-mail: bobhogg@cfenet.ubc.ca

    Affiliations: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada, Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

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  • David R Bangsberg,

    Affiliation: Epidemiology and Prevention Interventions Center, Division of Infectious Diseases and the Positive Health Program, San Francisco General Hospital, San Francisco, California, United States of America

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  • Viviane D Lima,

    Affiliation: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada

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  • Chris Alexander,

    Affiliation: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada

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  • Simon Bonner,

    Affiliation: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada

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  • Benita Yip,

    Affiliation: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada

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  • Evan Wood,

    Affiliation: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada

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  • Winnie W. Y Dong,

    Affiliation: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada

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  • Julio S. G Montaner,

    Affiliations: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

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  • P. Richard Harrigan

    Affiliations: British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada, Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

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  • Published: September 19, 2006
  • DOI: 10.1371/journal.pmed.0030356

About the Authors

Robert S Hogg, Viviane D Lima, Chris Alexander, Simon Bonner, Benita Yip, Evan Wood, Winnie W. Y Dong, Julio S. G Montaner, P. Richard Harrigan
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada
Robert S Hogg, Julio S. G Montaner
Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
Robert S Hogg
Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
David R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases and the Positive Health Program, San Francisco General Hospital, San Francisco, California, United States of America
P. Richard Harrigan
Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

Corresponding Author

Email: bobhogg@cfenet.ubc.ca

Competing Interests

RSH, DRB, CA, EW, JSGM, and PRH have received honorariums, travel grants to attend conferences, and research grants from pharmaceutical companies working in the area of HIV/AIDS.

Author Contributions

RSH, DRB, VDL, CA, SB, EW, JSGM, and PRH designed the study. RSH, BY, WWYD, and PRH participated in data gathering. VDL and SB participated in statistical analysis. RSH, DRB, VDL, CA, SB, BY, EW, WWYD, JSGM, and PRH contributed to writing the paper.