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Research Article

Reduced Antibody Responses to Vaccinations in Children Exposed to Polychlorinated Biphenyls

  • Carsten Heilmann,

    Affiliation: Paediatric Clinic II, National University Hospital, Rigshospitalet, Copenhagen, Denmark

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  • Philippe Grandjean mail,

    To whom correspondence should be addressed. E-mail: pgrand@hsph.harvard.edu

    Affiliations: Institute of Public Health, University of Southern Denmark, Odense, Denmark, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America

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  • Pál Weihe,

    Affiliations: Institute of Public Health, University of Southern Denmark, Odense, Denmark, Department of Occupational Medicine and Public Health, Tórshavn, Faroe Islands, Denmark

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  • Flemming Nielsen,

    Affiliation: Institute of Public Health, University of Southern Denmark, Odense, Denmark

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  • Esben Budtz-Jørgensen

    Affiliations: Institute of Public Health, University of Southern Denmark, Odense, Denmark, Department of Biostatistics, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark

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  • Published: August 22, 2006
  • DOI: 10.1371/journal.pmed.0030311

About the Authors

Carsten Heilmann
Paediatric Clinic II, National University Hospital, Rigshospitalet, Copenhagen, Denmark
Philippe Grandjean, Pál Weihe, Flemming Nielsen, Esben Budtz-Jørgensen
Institute of Public Health, University of Southern Denmark, Odense, Denmark
Philippe Grandjean
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
Pál Weihe
Department of Occupational Medicine and Public Health, Tórshavn, Faroe Islands, Denmark
Esben Budtz-Jørgensen
Department of Biostatistics, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark

Corresponding Author

Email: pgrand@hsph.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

CH, PG, PW, and EBJ designed the study. CH and PW supervised the clinical sampling. FN conducted the chemical analyses. EBJ did the statistical analyses. CH, PG, PW, FN, and EBJ wrote the paper.