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Research Article

Insensitivity of Paediatric HIV-1 Subtype C Viruses to Broadly Neutralising Monoclonal Antibodies Raised against Subtype B

  • Elin Solomonovna Gray,

    Affiliation: AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa

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  • Tammy Meyers,

    Affiliation: Harriet Shezi Clinic, University of the Witwatersrand, Johannesburg, South Africa

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  • Glenda Gray,

    Affiliation: Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa

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  • David Charles Montefiori,

    Affiliation: Duke University Medical Centre, Durham, North Carolina, United States of America

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  • Lynn Morris mail

    To whom correspondence should be addressed. E-mail: lynnm@nicd.ac.za

    Affiliation: AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa

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  • Published: July 18, 2006
  • DOI: 10.1371/journal.pmed.0030255

About the Authors

Elin Solomonovna Gray, Lynn Morris
AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
Tammy Meyers
Harriet Shezi Clinic, University of the Witwatersrand, Johannesburg, South Africa
Glenda Gray
Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
David Charles Montefiori
Duke University Medical Centre, Durham, North Carolina, United States of America

Corresponding Author

Email: lynnm@nicd.ac.za

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ESG and LM designed the study. ESG and LM analyzed the data. TM and GG enrolled patients. DM provided reagents and technical advice. ESG, TM, GG, DM, and LM contributed to writing the paper. ESG collected data and performed experiments for the study.